High correlation of estimated local conduction velocity with natural logarithm of bipolar electrogram amplitude in the reentry circuit of atrial flutter

Journal of Cardiovascular Electrophysiology
Taihei ItohKen Okumura

Abstract

Low conduction velocity (CV) in the area showing low electrogram amplitude (EA) is characteristic of reentry circuit of atypical atrial flutter (AFL). The quantitative relationship between CV and EA remains unclear. We characterized AFL reentry circuit in the right atrium (RA), focusing on the relationship between local CV and bipolar EA on the circuit. We investigated 26 RA AFL (10 with typical AFL; 10 atypical incisional AFL; 6 atypical nonincisional AFL) using CARTO system. By referring to isochronal and propagation maps delineated during AFL, points activated faster on the circuit were selected (median, 7 per circuit). At the 196 selected points obtained from all patients, local CV measured between the adjacent points and bipolar EA were analyzed. There was a highly significant correlation between local CV and natural logarithm of EA (lnEA) (R(2) = 0.809, P < 0.001). Among 26 AFL, linear regression analysis of mean CV, calculated by dividing circuit length (152.3 ± 41.7 mm) by tachycardia cycle length (TCL) (median 246 msec), and mean lnEA, calculated by dividing area under curve of lnEA during one tachycardia cycle by TCL, showed y = 0.695 + 0.191x (where: y = mean CV, x = lnEA; R(2) = 0.993, P < 0.001). Local CV estimated...Continue Reading

References

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Citations

Jan 18, 2016·Computer Methods and Programs in Biomedicine·Tobias Georg OesterleinArmin Luik
Apr 26, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Sohail ZahidNatalia A Trayanova
Jan 1, 2017·Circulation. Arrhythmia and Electrophysiology·Decebal Gabriel LaţcuNadir Saoudi
May 20, 2016·Journal of Cardiovascular Electrophysiology·Takahiko KinjoKen Okumura
Jan 3, 2020·Journal of Cardiovascular Medicine·Antonio De SimoneIgnacio García-Bolao
May 16, 2018·JACC. Clinical Electrophysiology·Decebal Gabriel Laţcu, Nadir Saoudi
Jun 19, 2021·Circulation. Arrhythmia and Electrophysiology·Mathijs S van SchieNatasja M S de Groot

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