Abstract
Adherence to treatment with inhaled corticosteroids (ICS) is a critical determinant of asthma control. The objective of this study was to assess factors that determine adherence to ICS therapy in children with asthma. Fifty-eight children with asthma, aged 5 to 16 years, used ICS with or without a spacer for 3 months. Adherence rates as measured from questionnaires and canisters, asthma symptom scores, and inhalation technique scores were assessed every 30 days. The degree of supervision by caregivers was assessed at day 30. Adherence rates measured using canisters were lower at day 60 than at day 30 (P=0.044) and did not change thereafter (74.4%±17.4% at day 30, 66.5%±18.4% at day 60, and 67.4%±22.2% at day 90). Adherence rates at days 60 and 90 and during the total study period were significantly different when measured by using questionnaires versus canisters (P<0.001, P=0.022, and P=0.001, respectively). In the comparison of adherence rates repeatedly measured at days 30, 60, and 90 and adherence rates during the total study period among the 3 groups, adherence rates in the high-degree supervision group were significantly higher than those in the low-degree supervision group (82.0±16.0 vs. 66.1±14.5, 75.4±14.4 vs. 56.2±18.4...Continue Reading
References
Dec 1, 1995·Thorax·N A GibsonJ Y Paton
Dec 1, 1996·The Journal of Allergy and Clinical Immunology·H MilgromC Rand
Sep 26, 1997·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·B BenderC Rand
Jan 13, 1998·Current Opinion in Pediatrics·H Milgrom, B Bender
Feb 12, 2000·Chest·M G CochraneR H Ben-Joseph
Sep 22, 2000·Archives of Disease in Childhood·G JónassonP Mowinckel
Oct 13, 2000·American Journal of Respiratory and Critical Care Medicine·E F JuniperJ N Roberts
Dec 2, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·B BenderM Z Wamboldt
Mar 13, 2002·Chest·Steven M JuliusLeslie Hendeles
Oct 10, 2002·Allergy·C S Rand
Jul 25, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ketan ShethPaul M Dorinsky
Dec 9, 2004·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Shannon L O'ConnorFrederick S Wamboldt
Sep 2, 2005·Allergy·L HeinzerlingT Zuberbier
Nov 10, 2006·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Charlotte Suppli UlrikPeter P Plaschke
Dec 26, 2006·Respiratory Medicine·Angelo G CorsicoIsa Cerveri
Aug 19, 2007·Pediatrics·Bruce G BenderLening Zhang
Feb 5, 2008·Journal of Managed Care Pharmacy : JMCP·Frank L Urbano
Apr 22, 2008·Respirology : Official Journal of the Asian Pacific Society of Respirology·Scott W BurgessSunalene G Devadason
Sep 18, 2008·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Nulma Souto Jentzsch, Paulo Augusto Moreira Camargos
Sep 30, 2008·Journal of Tropical Pediatrics·Laura LasmarMarina Carvalhais
Feb 3, 2009·Allergy·L LasmarJ A R Moura
May 7, 2009·Allergy·N S JentzschJ Bousquet
Feb 23, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Masaya TakemuraMotonari Fukui
Mar 26, 2011·Primary Care Respiratory Journal : Journal of the General Practice Airways Group·Angkana RoyJuan P Wisnivesky