High-density genetic linkage maps of Phytophthora infestans reveal trisomic progeny and chromosomal rearrangements

Genetics
T van der LeeF Govers

Abstract

Detailed analysis of the inheritance of molecular markers was performed in the oomycete plant pathogen Phytophthora infestans. Linkage analysis in the sexual progeny of two Dutch field isolates (cross 71) resulted in a high-density map containing 508 markers on 13 major and 10 minor linkage groups. The map showed strong clustering of markers, particularly of markers originating from one parent, and dissimilarity between the parental isolates on linkage group III in the vicinity of the mating-type locus, indicating a chromosomal translocation. A second genetic map, constructed by linkage analysis in sexual progeny of two Mexican isolates (cross 68), contained 363 markers and is thus less dense than the cross 71 map. For some linkage groups the two independent linkage maps could be aligned, but sometimes markers appeared to be in a different order, or not linked at all, indicating chromosomal rearrangements between genotypes. Graphical genotyping showed that some progeny contained three copies of a homologous linkage group. This trisomy was found for several linkage groups in both crosses. Together, these analyses suggest a genome with a high degree of flexibility, which may have implications for evolution of new races and resist...Continue Reading

References

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Citations

Oct 31, 2007·Current Genetics·Willem A Man In 't VeldHarold J G Meijer
Jun 19, 2008·Proceedings of the National Academy of Sciences of the United States of America·Syuzanna R HarutyunyanFrancine Govers
Mar 24, 2005·Molecular Plant-microbe Interactions : MPMI·Thomas A RandallHoward S Judelson
Feb 11, 2005·Eukaryotic Cell·James A FraserJoseph Heitman
Mar 22, 2008·Genome Génome / Conseil National De Recherches Canada·S W Chang, G Jung
Dec 8, 2005·Canadian Journal of Microbiology·Yu-Huan Gu, Wen-Hsiung Ko
Jan 29, 2011·Fungal Genetics and Biology : FG & B·Annelies VercauterenKurt Heungens
Aug 19, 2008·Molecular Plant Pathology·William Fry
Mar 12, 2010·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Mursel CatalGerard C Adams
Feb 4, 2006·Fungal Genetics and Biology : FG & B·Jun GuoFrancine Govers
Jan 15, 2013·Journal of Microbiological Methods·Ying LiTheo van der Lee
Sep 5, 2006·Current Biology : CB·Joseph Heitman
Oct 5, 2010·Fungal Genetics and Biology : FG & B·Thomas L KubisiakC Dana Nelson
Dec 14, 2016·Molecular Plant-microbe Interactions : MPMI·Ying LiSanwen Huang
Nov 30, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·C J PozniakJ M Clarke
Jun 19, 2010·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·K WiebeC J Pozniak

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