PMID: 9174476Jun 1, 1997Paper

High dietary calcium intakes reduce zinc absorption and balance in humans

The American Journal of Clinical Nutrition
R J Wood, J J Zheng

Abstract

Optimal calcium intakes of 37.5 mmol(1500 mg)/d have been proposed for elderly people. We investigated the effects of calcium supplementation on zinc absorption and balance in 18 relatively healthy, postmenopausal women aged 59-86 y. All subjects received a standardized basal diet of typical foods supplying 269 mumol (17.6 mg) Zn/d and 22.2 mmol (890 mg) Ca/d during the 36-d study. In two of three experimental periods, an additional 11.7 mmol (468 mg) Ca/d as either milk or an inorganic calcium phosphate supplement was provided. Net zinc absorption and zinc balance were significantly reduced by approximately 2 mg/d during both high-calcium treatments. In a second study, conducted in a separate group of men and women aged 21-69 y, a whole-gut lavage, zinc-absorption test was used to investigate the acute effect of a 15-mmol CaCO3 (600 mg Ca) supplement, with and without extra zinc, on zinc absorption from a single test meal supplying 111.7 mumol (7.3 mg) Zn. Zinc absorption was reduced significantly by 50% when the calcium supplement was given with the meal. Inclusion of an extra 119.3 mumol (7.8 mg) Zn as part of a calcium supplement offset the detrimental effect of calcium on zinc absorption. Our findings suggest that high-cal...Continue Reading

Citations

Apr 19, 2003·International Journal of Food Sciences and Nutrition·F Cámara, M A Amaro
Apr 18, 2014·Nutrition Reviews·Silvia Bel-SerratUNKNOWN EURRECA Network
Jun 24, 2017·The British Journal of Nutrition·Jonathan StockmanPenelope J Morris
Oct 16, 2007·Digestive Diseases and Sciences·Mohammed R JafriLee J Melton
Jan 6, 2012·Public Health Nutrition·Marta MesíasM Pilar Navarro
Feb 28, 2015·Paediatrics & Child Health·Audrey BeringerChristina Vadeboncoeur
Jul 19, 2017·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Ann Katrin SauerAndreas M Grabrucker
Oct 16, 2003·Journal of the American College of Nutrition·Theresa A Nicklas
Jul 27, 2001·Food Additives and Contaminants·C TerrésM C López
Jun 1, 1998·Nutrition Research Reviews·R S Gibson, E L Ferguson
Mar 19, 2002·Veterinary Dermatology·Philip Roudebush, Karen J Wedekind
Aug 22, 2007·Biological Trace Element Research·Satoshi TakasugiHideo Yano
May 24, 2012·The British Journal of Nutrition·Leland V MillerK Michael Hambidge
Apr 17, 2015·Neural Plasticity·Guillermo VelaAndreas M Grabrucker
Sep 29, 2020·Annals of the New York Academy of Sciences·Cristina PalaciosAna Pilar Betrán
Jan 10, 2012·Age·Eugenio MocchegianiAscension Marcos
Aug 1, 2014·Plant Foods for Human Nutrition·María Gimena Galán, Silvina Rosa Drago
Nov 16, 2011·European Eating Disorders Review : the Journal of the Eating Disorders Association·Florian Daniel ZepfLars Wöckel
Jan 17, 2017·Pediatric Gastroenterology, Hepatology & Nutrition·Tae Hwan HanYong Joo Kim
Dec 30, 2020·International Journal of Environmental Research and Public Health·Sylvia A TakyiJulius N Fobil
Sep 2, 2003·The Journal of Nutrition·Steven A Abrams, Stephanie A Atkinson
Mar 18, 2000·The Journal of Nutrition·H H Sandstead
Mar 23, 2021·Journal of Clinical Orthopaedics and Trauma·Binoti ShethAkash Jain
Aug 2, 2001·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·H TapieroK D Tew
Mar 4, 2003·Gastroenterology·Charles N BernsteinMeryl S Leboff
Jul 3, 2021·Animals : an Open Access Journal From MDPI·Jujhar AtwalPhillip Watson
Mar 15, 2003·Gastroenterology Clinics of North America·Elie Hamaoui, Michal Hamaoui
Jul 3, 1998·Gastroenterology Clinics of North America·J R Saltzman, R M Russell

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