High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug.

Parasite : Journal De La Société Française De Parasitologie
O ChosidowGiao Do-Pham

Abstract

We highlight the absence of high-level evidence from dose-ranging studies regarding the use of oral ivermectin in susceptible parasitic diseases. We provide published data supporting the use of a higher dosage regimen of ivermectin in malaria and difficult-to-treat head lice, and announce an ongoing randomized clinical trial in severe scabies.

References

Apr 21, 2006·The New England Journal of Medicine·Olivier Chosidow
Feb 26, 2010·The New England Journal of Medicine·Bart J Currie, James S McCarthy
Mar 12, 2010·The New England Journal of Medicine·Olivier ChosidowIan Burgess
Dec 10, 2015·The New England Journal of Medicine·Lucia RomaniAndrew C Steer
Sep 25, 2017·The Lancet Infectious Diseases·Chante KarimkhaniRobert P Dellavalle
Sep 25, 2017·The Lancet Infectious Diseases·Olivier Chosidow, L Claire Fuller
Jan 19, 2018·PLoS Neglected Tropical Diseases·Jose MuñozAlejandro J Krolewiecki

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Clinical Trials Mentioned

NCT02841215

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