High dose methylphenidate treatment in adult attention deficit hyperactivity disorder: a case report.

Journal of Medical Case Reports
Michael LiebrenzDominique Eich

Abstract

Stimulant medication improves hyperactivity, inattention, and impulsivity in both pediatric and adult populations with Attention Deficit Hyperactivity Disorder (ADHD). However, data regarding the optimal dosage in adults is still limited. We report the case of a 38-year-old Caucasian patient who was diagnosed with Attention Deficit Hyperactivity Disorder when he was nine years old. He then received up to 10 mg methylphenidate (Ritalin®) and 20 mg sustained-release methylphenidate (Ritalin SR®) daily. When he was 13, his medication was changed to desipramine (Norpramin®), and both Ritalin® and Ritalin SR® were discontinued; and at age 18, when he developed obsessive-compulsive symptoms, his medication was changed to clomipramine (Anafranil®) 75 mg daily. Still suffering from inattention and hyperactivity, the patient began college when he was 19, but did not receive stimulant medication until three years later, when Ritalin® 60 mg daily was re-established. During the 14 months that followed, he began to use Ritalin® excessively, both orally and rectally, in dosages from 4800-6000 mg daily. Four years ago, he was referred to our outpatient service, where his Attention Deficit Hyperactivity Disorder was re-evaluated. At that point...Continue Reading

References

Feb 22, 2003·Journal of the American Academy of Child and Adolescent Psychiatry·Wendy Klein-Schwartz, Jean McGrath
Jan 8, 2004·Journal of Clinical Psychopharmacology·Stephen V FaraoneJoseph Biederman
Apr 15, 2004·The Journal of Pharmacology and Experimental Therapeutics·Zejin SunWilliam F Bosron
Jan 2, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Jon McClellanUNKNOWN Work Group on Quality Issues
Jun 22, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Steven Pliszka, UNKNOWN AACAP Work Group on Quality Issues
Mar 22, 2008·Archives of Disease in Childhood. Education and Practice Edition·V A Harpin
Sep 26, 2008·BMJ : British Medical Journal·Tim KendallUNKNOWN Guideline Development Group
Oct 7, 2008·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Stephen V Faraone, Kevin M Antshel
Sep 2, 2009·Neuropsychiatric Disease and Treatment·Rajasree Nair, Shannon B Moss
Sep 8, 2009·Neuropharmacology·Zsofia NemodaMaria Sasvari-Szekely
Jun 5, 2010·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Michael RöslerJan Buitelaar
Mar 25, 2011·Attention Deficit and Hyperactivity Disorders·K KlampflM Gerlach
Mar 25, 2011·Attention Deficit and Hyperactivity Disorders·Jasmin BartlEdna Grünblatt
Jun 24, 2011·Current Psychiatry Reports·Paul G HammernessAshley Chilton
Oct 11, 2011·Swiss Medical Weekly·Marcel BruggisserMatthias E Liechti
Dec 14, 2011·JAMA : the Journal of the American Medical Association·Laurel A HabelJoe V Selby

❮ Previous
Next ❯

Citations

Aug 6, 2014·Journal of Pharmacy Practice·Gyula Bokor, Peter D Anderson
Jan 1, 2014·Journal of Investigative Medicine High Impact Case Reports·Nicoleta StoiceaSergio Bergese

❮ Previous
Next ❯

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.