High efficacy with deep nurse-administered propofol sedation for advanced gastroenterologic endoscopic procedures

Endoscopy International Open
Jeppe Thue JensenPeter Vilmann

Abstract

Whereas data on moderate nurse-administered propofol sedation (NAPS) efficacy and safety for standard endoscopy is abundant, few reports on the use of deep sedation by endoscopy nurses during advanced endoscopy, such as Endoscopic Retrograde Cholangiopancreatography (ERCP) and Endoscopic Ultrasound (EUS) are available and potential benefits or hazards remain unclear. The aims of this study were to investigate the efficacy of intermittent deep sedation with propofol for a large cohort of advanced endoscopies and to provide data on the safety. All available data from patients sedated with intermittent deep NAPS for ERCP, EUS or double balloon enteroscopy (DBE, since the method was implemented in May 2007 through December 2012 were included for evaluation in a retrospective case-control design. Data from 1899 patients undergoing 1899 procedures were included for evaluation. All but one procedure were completed with intermittent deep NAPS. The mean propofol dose was 397 mg (SD: 232.4) and the infusion rate was 23.9 mg/kg. The frequency of hypoxia was 4.3 % and 20 patients needed assisted ventilation (1.1 %). Anesthesiologic support was requested eight times (0.4 %). One patient was intubated due to suspected aspiration. Intermitten...Continue Reading

Citations

May 17, 2017·Current Opinion in Anaesthesiology·Michael KernSascha Tank
Apr 6, 2018·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Enrique Pérez-Cuadrado-RoblesJesús García-Cano
Mar 14, 2021·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·Theodor VoiosuIoan Sporea

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