High-energy transurethral thermotherapy with CoreTherm approaches transurethral prostate resection in outcome efficacy: a meta-analysis

Journal of Endourology
Jonathan D KayeMichael C Ost

Abstract

Minimally invasive office-based treatments for benign prostatic hyperplasia (BPH) are challenging the traditional surgical and medical management options for symptomatic BPH. We conducted a meta-analysis of published randomized controlled trials that compared high-energy transurethral microwave thermotherapy (HE-TUMT) with transurethral resection of the prostate (TURP) to compare subjective and objective outcomes. A literature search using Pub-Med was conducted to obtain all published data on HE-TUMT and all randomized controlled trials that compared HE-TUMT with TURP. Data were analyzed focusing on the pretreatment and posttreatment end points of the International Prostate Symptom Score(IPSS), maximum flow rate (Q(max)), and postvoid residual (PVR). A meta-analysis was conducted, and data were stratified with respect to the type of HE-TUMT machinery used. A total of 458 patients were studied. Differences in IPSS, Q(max), and PVR from current trials that compared TURP with HE-TUMT are best evaluated at 1-year follow-up. At this time point, changes in Q(max) (P < 0.001), IPSS (P = 0.01), and PVR (P = 0.02) are more significant if TURP is the management mode. HE-TUMT with the CoreTherm() device demonstrates the most significant i...Continue Reading

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Citations

Dec 25, 2009·Der Urologe. Ausg. A·O ReichC Stief
Jul 6, 2010·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Thomas P RyanBrianne Hamilton
Nov 15, 2011·Current Opinion in Urology·Bob DjavanYakup Bostanci
Apr 1, 2020·Lower Urinary Tract Symptoms·Özbay EnginÖncel Halil Ferat
Jan 21, 2011·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Evangelos LiatsikosJens-Uwe Stolzenburg

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