High fat, low carbohydrate, enteral feeding lowers PaCO2 and reduces the period of ventilation in artificially ventilated patients

Intensive Care Medicine
N M al-SaadyE D Bennett

Abstract

The objective of this study was to compare the effect of a high fat, low carbohydrate enteral feed with a standard isocaloric, isonitrogenous enteral feed on PaCO2 and ventilation time in patients with acute respiratory failure requiring artificial ventilation. 20 clinically stable patients requiring enteral feeding were randomized to either feed in a double-blind fashion. Initial ventilator standard settings were adjusted according to clinical state. Measurements including minute volume and arterial blood gases were made twice daily. Weaning was carried out according to set criteria. During the feeding period, PaCO2 just prior to weaning fell by 16% in the high fat group but increased by 4% in the standard feed group (p = 0.003). The high fat group spent a mean of 62 h less time on the ventilator (p = 0.006). A high fat, low carbohydrate enteral feed appears to be beneficial in patients undergoing artificial ventilation.

Associated Clinical Trials

References

Aug 12, 1976·The New England Journal of Medicine·R C DoekelJ V Weil
Jun 1, 1988·The American Review of Respiratory Disease·C Deschamps, J R Rodarte
Mar 1, 1981·JPEN. Journal of Parenteral and Enteral Nutrition·H R Bassili, M Deitel
Nov 1, 1981·Annals of Internal Medicine·H D CovelliJ F Beekman
Mar 1, 1982·Critical Care Medicine·J AskanaziJ M Kinney

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Citations

Oct 7, 2011·JAMA : the Journal of the American Medical Association·Todd W RiceUNKNOWN NIH NHLBI Acute Respiratory Distress Syndrome Network of Investigators
May 3, 2013·Current Gastroenterology Reports·Karen S AllenRodrigo Cavallazzi
Jan 1, 1996·Nutrition·M A McCamishB C Abbruzzese
Jun 1, 1997·Disease-a-month : DM·B A Mizock, S Troglia
Jul 3, 1998·Gastroenterology Clinics of North America·R C DeWitt, K A Kudsk
Jan 1, 1989·Intensive Care Medicine·G Iapichino
Aug 1, 1994·Intensive Care Medicine·B van den BergW C Hop
Aug 1, 1994·Intensive Care Medicine·N M al-Saady
Sep 1, 2005·Intensive Care Medicine·Gerald HuschakRalph Stuttmann
Jan 30, 2016·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Meng-Jer HsiehYing-Huang Tsai
Jul 12, 2011·Critical Care Clinics·Anna KrzakLena M Napolitano
Aug 19, 2007·The Veterinary Clinics of North America. Small Animal Practice·Scott J Campbell
Jan 22, 2005·Nutrition·Abraham A Nisim, Alexander D Allins
Apr 17, 1999·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·D Radrizzani, G Iapichino
Aug 1, 1997·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·S KleinP Twomey
Aug 1, 1992·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·J J Payne-JamesD B Silk
Apr 6, 2004·Neurologic Clinics·Gary A Thomas, Milind J Kothari
Oct 11, 2005·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Ainsley M Malone
Dec 18, 2014·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Britta BrownMelanie Betz
Apr 1, 1994·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·L E Matarese
Jun 2, 2009·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Yimin Chen, Sarah J Peterson
Jan 10, 2008·Journal of Burn Care & Research : Official Publication of the American Burn Association·Theresa MayesRichard J Kagan
May 19, 2011·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Jennifer DoleyMichelle Sandberg
Jan 20, 2012·The Cochrane Database of Systematic Reviews·Bronwen MastersFiona Wood
Feb 12, 2019·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Karen Allen, Leah Hoffman
Apr 7, 2007·European Journal of Gastroenterology & Hepatology·Mahmood WahedJeremy Powell-Tuck
Dec 4, 2009·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Ainsley M Malone
Feb 14, 2002·JPEN. Journal of Parenteral and Enteral Nutrition·UNKNOWN ASPEN Board of Directors and the Clinical Guidelines Task Force
Jan 27, 2011·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Leslie A Hamilton, Kimberly A Trobaugh
Jul 11, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Mikiko WatanabeLucio Gnessi
Jun 20, 2001·European Journal of Anaesthesiology·G R Park, S Clarke
Aug 2, 2019·Current Gastroenterology Reports·Berkeley N LimketkaiKaren Allen
Apr 4, 2021·Nutrients·Elena GangitanoCarla Lubrano
Jan 1, 1991·Annales Françaises D'anesthèsie Et De Rèanimation·M RaucoulesD Grimaud

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