PMID: 11926572Apr 3, 2002Paper

High frequency of anti-endomysial reactivity in candidates to heart transplant

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Daniele PratiNorth Italy Transplant Programme Working Group (NITp)

Abstract

A possible link between coeliac disease and dilated cardiomyopathy has recently been suggested. . To assess the frequency of anti-endomysial antibodies, the marker for coeliac disease, in patients with different forms of heart failure, and to establish the clinical features of those endomysial antibody positive. . A total of 642 consecutive patients entering the waiting list for heart transplantation from 1995 through 1997 were studied. The prevalence of endomysial IgA antibodies, determined by indirect immunofluorescence, was compared to that observed in three surveys conducted in the Italian general population. Of the 642 patients, 12 (1.9%; 95% confidence interval 0.97-3.2) resulted endomysial antibody positive, versus 34/9,720 healthy controls (0.35%; 95% confidence interval, 0.23-0.47), accounting for a relative risk of 5.3 (95% confidence interval, 2.8-10.3). Anti-endomysial antibodies were found in 6/275 patients with dilated cardiomyopathy and 6/367 with other forms of heart failure (2.2% versus 1.6%; 95% confidence interval 0.8-4.7 and 0.6-3.5), with no statistical difference. The 12 endomysial antibody positive patients were leaner (body mass index, 22.0 +/- 1.9 vs 24.2 +/- 3. 1, p<0. 05) than 36 seronegative patients...Continue Reading

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Citations

Aug 26, 2010·Internal and Emergency Medicine·Elisa RomagnoliAntonello Pietrangelo
Aug 2, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·M CurioneM Barbato
Apr 3, 2002·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·D Schuppan, R Ciccocioppo
Jun 8, 2006·Digestive Diseases and Sciences·Ricardo Schmit T De BemHeda Maria Barska Dos Santos Amarante
Jul 15, 2015·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Louise EmilssonJonas F Ludvigsson
Nov 4, 2008·Journal of Pediatric Gastroenterology and Nutrition·Margherita BonamicoUNKNOWN Società Italiana di Gastroenterologica, Epatologia, e Nutrizione Pediatrica
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Feb 4, 2006·Journal of Pediatric Gastroenterology and Nutrition·Margherita BonamicoClaudio Tiberti
Jul 9, 2008·Scandinavian Journal of Clinical and Laboratory Investigation·Enrico VizzardiAlberto Lanzini
Aug 30, 2008·Journal of Pediatric Gastroenterology and Nutrition·Raffaella NennaMargherita Bonamico
Jun 19, 2018·Scandinavian Journal of Gastroenterology·Rishi BoliaUjjal Poddar

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