Abstract
A possible link between coeliac disease and dilated cardiomyopathy has recently been suggested. . To assess the frequency of anti-endomysial antibodies, the marker for coeliac disease, in patients with different forms of heart failure, and to establish the clinical features of those endomysial antibody positive. . A total of 642 consecutive patients entering the waiting list for heart transplantation from 1995 through 1997 were studied. The prevalence of endomysial IgA antibodies, determined by indirect immunofluorescence, was compared to that observed in three surveys conducted in the Italian general population. Of the 642 patients, 12 (1.9%; 95% confidence interval 0.97-3.2) resulted endomysial antibody positive, versus 34/9,720 healthy controls (0.35%; 95% confidence interval, 0.23-0.47), accounting for a relative risk of 5.3 (95% confidence interval, 2.8-10.3). Anti-endomysial antibodies were found in 6/275 patients with dilated cardiomyopathy and 6/367 with other forms of heart failure (2.2% versus 1.6%; 95% confidence interval 0.8-4.7 and 0.6-3.5), with no statistical difference. The 12 endomysial antibody positive patients were leaner (body mass index, 22.0 +/- 1.9 vs 24.2 +/- 3. 1, p<0. 05) than 36 seronegative patients...Continue Reading
References
Oct 1, 1986·Pathology, Research and Practice·B ChuaquiP Casanegra
Jan 22, 1994·Lancet·C CatassiP L Giorgi
Mar 24, 1994·The New England Journal of Medicine·G Opelz, T Wujciak
Jul 1, 1996·Gut·S A McMillanA E Evans
Jul 1, 1997·Nature Medicine·W DieterichD Schuppan
Sep 23, 1997·Scandinavian Journal of Gastroenterology·G R CorazzaG Gasbarrini
Jul 20, 1999·The Journal of Biological Chemistry·K SmallS B Liggett
Jul 27, 1999·Lancet·M CurioneE Cardi
Sep 4, 1999·Lancet·K MustalahtiM Mäki
Nov 5, 1999·Human Reproduction·G F MeloniS Musumeci
Sep 7, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·O KordonouriT Danne
Feb 24, 2001·Nursing Standard·A Sullivan
Citations
Aug 26, 2010·Internal and Emergency Medicine·Elisa RomagnoliAntonello Pietrangelo
Aug 2, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·M CurioneM Barbato
Apr 3, 2002·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·D Schuppan, R Ciccocioppo
Jan 1, 2011·BMJ Case Reports·Juan P BarrioDerliz Mereles
Jun 8, 2006·Digestive Diseases and Sciences·Ricardo Schmit T De BemHeda Maria Barska Dos Santos Amarante
Jul 15, 2015·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Louise EmilssonJonas F Ludvigsson
Oct 24, 2007·Journal of Internal Medicine·P ElfströmJ F Ludvigsson
Dec 5, 2012·ISRN Gastroenterology·Berna SaylanGonca Ustundag
Nov 4, 2008·Journal of Pediatric Gastroenterology and Nutrition·Margherita BonamicoUNKNOWN Società Italiana di Gastroenterologica, Epatologia, e Nutrizione Pediatrica
Dec 29, 2007·Alimentary Pharmacology & Therapeutics·L WeiT M MacDonald
Feb 4, 2006·Journal of Pediatric Gastroenterology and Nutrition·Margherita BonamicoClaudio Tiberti
Jan 1, 2010·Clinical Cardiology·Konstantinos MavroudisChariton Antonakoudis
Jul 9, 2008·Scandinavian Journal of Clinical and Laboratory Investigation·Enrico VizzardiAlberto Lanzini
Aug 30, 2008·Journal of Pediatric Gastroenterology and Nutrition·Raffaella NennaMargherita Bonamico
Jun 19, 2018·Scandinavian Journal of Gastroenterology·Rishi BoliaUjjal Poddar