High frequency of secondary, but not primary ocular manifestations of inflammatory bowel disease in patients treated at a tertiary care center

European Journal of Gastroenterology & Hepatology
Jens WalldorfThomas Hammer

Abstract

Ocular manifestations of inflammatory bowel disease (IBD) are relevant complications of IBD. Only a few prospective studies are available on the characteristics of these manifestations. The aim of this study was to characterize the frequency of eye disease in patients with IBD, including primary and secondary ocular manifestations of IBD, and to identify patients who may need specialized ophthalmologic care. In a prospective observational study, patients with IBD were examined for ocular symptoms in comparison with control participants without IBD. All patients with IBD underwent a thorough ophthalmologic examination (including slit-lamp, tonometry, tear breakup time, Schirmer's test, and coherence tomography). The results were analyzed with respect to sociodemographic and disease-related characteristics. A total of 61 patients (33 women, 39 Crohn's disease, 22 ulcerative colitis, age 43.3±12.9 years, disease duration 12.4±9.3 years) were included. Ophthalmologic symptoms were reported by 53 patients (86.9%, most frequently deterioration of vision 42.6%, foreign body sensation 36.1%) compared with 60.6% in healthy controls (P=0.001). A clinically relevant, previously undetected ophthalmologic diagnosis was identified in 56 pati...Continue Reading

References

Apr 1, 1991·Ophthalmology·J F SalmonA D Murray
Aug 1, 1974·The British Journal of Ophthalmology·D J HopkinsJ C Goligher
Jan 5, 2002·Scandinavian Journal of Gastroenterology·C SalvaraniUNKNOWN European Collaborative IBD Study Group
Nov 12, 2003·Survey of Ophthalmology·Faruque D Ghanchi, Bjorn J Rembacken
Jan 31, 2007·International Journal of Colorectal Disease·Safiye YilmazBelkis Unsal
Oct 29, 2009·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·A G SchreyerUNKNOWN Deutsche Gesellschaft für Verdauungs-und Stoffwechselkrankheiten, Kompetenznetzwerks CED (Chronisch entzündliche Darmerkrank
Dec 10, 2009·Inflammatory Bowel Diseases·Dídia Bismara Cury, Alan C Moss
Sep 3, 2010·The American Journal of Gastroenterology·Stephan R VavrickaAlain M Schoepfer
Apr 1, 2011·Investigative Ophthalmology & Visual Science·Kelly K NicholsDavid A Sullivan
Nov 28, 2013·Inflammatory Bowel Diseases·Federica Fasci-SpurioJack Satsangi
Dec 5, 2014·Zeitschrift für Gastroenterologie·J C PreißJ C Hoffmann
Apr 17, 2015·TheScientificWorldJournal·Rana MadySalim Butrus
Jun 6, 2015·BMC Ophthalmology·Alexandre MatetJean-Louis Bourges

❮ Previous
Next ❯

Citations

Jun 14, 2019·Therapeutic Advances in Gastroenterology·Sarah E ShannahanMark A Peppercorn
Mar 7, 2020·Frontline Gastroenterology·Lema Imam, Hasan Nadim Haboubi

❮ Previous
Next ❯

Software Mentioned

SPSS
PASW Statistics
Excel

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.