High Frequency of Sleep Disorders in Parkinson's Disease and Its Relationship with Quality of Life

European Neurology
Manoel Alves Sobreira-NetoAlan Luiz Eckeli

Abstract

To determine the frequency of major sleep disorders in patients with Parkinson's disease (PD), diagnosed according to the third international classification of sleep disorders, and assess the relationship of those disorders with the quality of life. A cross-sectional study was performed involving 88 consecutive patients with PD from outpatient clinic. Participants were subjected to clinical interviews, assessment using standardized scales (Epworth Sleepiness Scale, PD Questionnaire, Pittsburgh sleep quality index (PSQI) and, for individuals with a diagnosis of RLS/WED, International RLS/WED grading scale), and video-polysomnography. We observed sleep disorders in 96.5% of the participants, with REM-sleep behavior disorder found in 62.5%, obstructive sleep apnea in 62.5%, insomnia in 55.7%, and restless legs syndrome in 28.4%. We observed a correlation between health-related quality of life with the PSQI and the Epworth sleepiness scale. Patients with PD have a high prevalence of sleep disorders. The quality of sleep and excessive daytime sleepiness significantly affect the quality of life in these individuals.

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Citations

Nov 22, 2018·Neurological Research·Manoel Alves Sobreira-NetoAlan Luiz Eckeli
Apr 18, 2018·Chinese Medical Journal·Yun ShenChun-Feng Liu
Jan 13, 2019·Psychiatry and Clinical Neurosciences·Emmanuelle S T SobreiraVitor Tumas
Sep 26, 2019·Arquivos de neuro-psiquiatria·Manoel Alves Sobreira-NetoAlan Luiz Eckeli
Jun 20, 2019·Journal of Geriatric Psychiatry and Neurology·Manoel Alves Sobreira-NetoAlan Luiz Eckeli
Apr 8, 2020·Movement Disorders Clinical Practice·Douglas M WallaceRobert A Hauser
Jul 18, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Jun ZhuLi Zhang
Aug 9, 2018·Frontiers in Neurology·Luigi Ferini-StrambiAndrea Galbiati
May 8, 2019·Movement Disorders Clinical Practice·Pablo Martinez-MartinFrancisco Vivancos
Oct 13, 2020·Journal of Geriatric Psychiatry and Neurology·Diego Santos-GarcíaP Martinez-Martin
Dec 8, 2020·PloS One·Heide Baumann-VogelChristian R Baumann
Mar 4, 2021·Arquivos de neuro-psiquiatria·Manoel Alves Sobreira-NetoAlan Luiz Eckeli
Mar 17, 2021·Chinese Medical Journal·Xiang-Yang CaoChun-Feng Liu
Mar 18, 2021·Curēus·Maithrayie Kumaresan, Safeera Khan
Mar 24, 2021·Movement Disorders : Official Journal of the Movement Disorder Society·Carlos M O de AlmeidaAlan L Eckeli
Mar 24, 2021·Sleep Medicine·Claudio LiguoriAlessandra Di Pucchio
Nov 25, 2021·Journal of Neurophysiology·Yasmin C AquinoAna C Takakura

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