High-frequency repetitive transcranial magnetic stimulation (rTMS) improves neurocognitive function in bipolar disorder

Journal of Affective Disorders
Lin-Lin YangYu-Mei Wang

Abstract

Patients with bipolar disorder (BD) present widespread and significant neurocognitive impairments during all stages of the disorder. Repetitive transcranial magnetic stimulation (rTMS) has been used to improve clinical outcomes in common psychiatric diseases, such as depression, anxiety disorders, schizophrenia, and BD. Whether rTMS can improve cognitive function in BD patients remains unclear. The present study explored the regulatory effects of rTMS on cognitive function in patients with BD. Fifty-two eligible subjects with BD were randomly assigned to receive active or sham rTMS via high-speed magnetic stimulator with a figure-of-eight coil for 10 consecutive days. In the active rTMS group, a total of 25,000 stimuli were applied over the left dorsolateral prefrontal cortex at 110% of the motor threshold. The sham group received corresponding sham stimulation. Clinical manifestations and cognitive functions were assessed using a modified 24-item Hamilton Depression Rating Scale (HDRS), the Young Mania Rating Scale (YMRS), and the MATRICS Consensus Cognitive Battery (MCCB). Ten consecutive days of high-frequency active rTMS improved scores on the Wechsler Memory Scale-III Spatial Span, and the MCCB Category Fluency subtest, wi...Continue Reading

References

Nov 1, 1978·The British Journal of Psychiatry : the Journal of Mental Science·R C YoungD A Meyer
May 1, 1986·Archives of General Psychiatry·C MazureL H Price
Jan 1, 1995·Annals of Epidemiology·M E FarmerD A Regier
Dec 22, 1999·Psychotherapy and Psychosomatics·A Martínez-AránM Salamero
Apr 3, 2001·Annual Review of Neuroscience·E K Miller, J D Cohen
May 23, 2001·Psychiatry Research·J K ZubietaB J Giordani
Oct 2, 2001·The American Journal of Psychiatry·L ClarkG M Goodwin
Apr 2, 2002·The British Journal of Psychiatry : the Journal of Mental Science·Luke ClarkGuy M Goodwin
May 25, 2002·Psychological Medicine·J S RubinszteinB J Sahakian
Aug 10, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·W GerschlagerJ C Rothwell
May 18, 2004·European Archives of Psychiatry and Clinical Neuroscience·Luke Clark, Guy M Goodwin
Nov 9, 2004·Schizophrenia Research·Michael F Green, Keith H Nuechterlein
Nov 9, 2004·Schizophrenia Research·Keith H NuechterleinRobert K Heaton
May 4, 2005·Trends in Cognitive Sciences·Kevin N Ochsner, James J Gross
Jan 3, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Katsuyuki MachiiAlvaro Pascual-Leone
May 9, 2006·Journal of Affective Disorders·Lucy J RobinsonP Brian Moore
Aug 10, 2007·The Journal of Clinical Psychiatry·Maria MurEduard Vieta
Jan 4, 2008·The American Journal of Psychiatry·Robert S KernStephen R Marder
Jan 4, 2008·The American Journal of Psychiatry·Keith H NuechterleinStephen R Marder
Sep 20, 2008·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Sofia BrissosFlávio Kapczinski
Oct 6, 2009·Journal of Affective Disorders·Scott A LangeneckerMelvin G McInnis
Oct 17, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Simone RossiUNKNOWN Safety of TMS Consensus Group
Oct 28, 2009·Journal of Neural Transmission·Birgit GuseThomas Wobrock
Nov 26, 2010·Acta Psychiatrica Scandinavica·E BoraM Berk
Apr 1, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Katherine E BurdickAnil K Malhotra
Aug 16, 2011·NeuroImage·R Andy McKinleyJeremy Nelson
Jan 7, 2015·The British Journal of Psychiatry : the Journal of Mental Science·Ioana A CristeaPim Cuijpers
Jul 15, 2015·Journal of the International Neuropsychological Society : JINS·Sarah H SperryKathryn E Lewandowski
Nov 27, 2015·Annals of General Psychiatry·Mădălina VrabieIoana Micluţia
Nov 28, 2015·European Archives of Psychiatry and Clinical Neuroscience·J VolkertA Reif
May 13, 2017·The International Journal of Neuropsychopharmacology·Brisa SoléEduard Vieta
Dec 3, 2017·Clinical Psychology Review·Isabela M M LimaSheri L Johnson
Apr 10, 2018·Journal of Affective Disorders·Martin L MyczkowskiAndre R Brunoni

❮ Previous
Next ❯

Citations

Sep 29, 2020·Annals of General Psychiatry·Konstantinos N Fountoulakis
Dec 8, 2020·Therapeutic Advances in Psychopharmacology·Danielle Hett, Steven Marwaha
Dec 7, 2020·Lancet·Roger S McIntyreRodrigo B Mansur
May 6, 2021·Bipolar Disorders·Gerasimos KonstantinouZafiris J Daskalakis
Aug 8, 2021·Psychiatry Research. Neuroimaging·Delphine Raucher-ChénéArthur Kaladjian

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here