PMID: 6106602Jul 1, 1980Paper

High hemoglobin levels during pregnancy and fetal risk

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
O KollerN Sagen

Abstract

In a series of 24 apparently uncomplicated pregnancies with small-for-dates newborn at or below the tenth percentile, 15 women had hemoglobin (Hb) levels 2 SD above the mean value of normal distribution in late pregnancy. Among these 15 was the only case with intrauterine death of unknown cause. In a series of 15 cases intrauterine fetal death of unknown cause, before start of labor 10 had Hb levels 2 SD above the mean, while in a series of 16 cases of late abortion where the fetus was alive until labor started, only one had a Hb level 2 SD above the mean. In three cases with serial Hb estimations, the levels were 2 SD above the mean one week or more before intrauterine fetal death. Two of these cases also had been observed during a successful pregnancy in which the Hb levels were within normal limits. It is concluded that high Hb levels during pregnancy may indicate a fetus at risk. High viscosity of the mother's blood may impede the uteroplacental circulation, casing placental infarction, growth retardation and ultimately fetal death.

References

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Citations

Jan 1, 1990·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·I Romslo
Mar 1, 1993·Asia-Oceania Journal of Obstetrics and Gynaecology·K EguchiY Hiramatsu
Oct 11, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·X XiongZ Guo
Jan 28, 2009·Scandinavian Journal of Clinical and Laboratory Investigation·Eszter VankySven M Carlsen
Jan 1, 2009·Indian Journal of Clinical Biochemistry : IJCB·Neeta KumarPratik Kumar
Jan 1, 1990·Drug Metabolism Reviews·E D Weinberg
Apr 1, 1991·Archives of Disease in Childhood·E Hemminki, U Rimpelä
Dec 22, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·J B RobinsJ J Walker
Jan 1, 1990·Acta Obstetricia Et Gynecologica Scandinavica·M Nordenvall, B Sandstedt
May 9, 2000·The American Journal of Clinical Nutrition·P J Steer
Feb 16, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·P H Rondó, A M Tomkins
Oct 1, 1982·British Journal of Obstetrics and Gynaecology·N SagenK Haram
Jun 27, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Odül A AmburgeyIra M Bernstein
Oct 12, 2013·Human Mutation·Celeste BentoUNKNOWN ECE-Consortium
Mar 31, 1984·British Medical Journal·C W Redman
Mar 31, 1984·British Medical Journal·C L Bakken, D S Young

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