High impact activity is related to lean but not fat mass: findings from a population-based study in adolescents.

International Journal of Epidemiology
Kevin DeereJon H Tobias

Abstract

Objective measures of physical activity calibrated against energy expenditure may have limited utility in studying relationships with musculoskeletal phenotypes. We wished to assess an alternative approach using an accelerometer calibrated according to impact loading. Of the 17-year olds from the Avon Longitudinal Study of Parents and Children (ALSPAC), 732 wore Newtest accelerometers while performing day-to-day activities for a mean of 5.8 days. Outputs were categorized as light, moderate, high and very high impact, based on the thresholds identified in 22 adolescents during graded activities. In subsequent regression analyses, activity data and fat mass were normalized by log transformation. The number of counts relating to high impact activity was ~2% that of light impact activity, and 33% greater in boys when compared with girls. High impact activity was more strongly related to lean mass [light: 0.033 (95% CI -0.023 to 0.089), moderate: 0.035 (95% CI -0.010 to 0.080) and high: 0.044 (95% CI 0.010 to 0.078)] (β = SD change in outcome per doubling in activity, height adjusted, boys and girls combined). In contrast, lower impact activity was more strongly related to fat mass [light: -0.069 (95% CI -0.127 to -0.011), moderate:...Continue Reading

References

Jul 1, 1985·Calcified Tissue International·C T Rubin, L E Lanyon
Mar 10, 2001·Paediatric and Perinatal Epidemiology·J GoldingUNKNOWN ALSPAC Study Team
Jul 6, 2004·Medicine and Science in Sports and Exercise·Kathleen F JanzTeresa A Marshall
Dec 7, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Cyrus CooperMark Hanson
Jan 13, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A VainionpääT Jämsä
Apr 7, 2007·Medicine and Science in Sports and Exercise·Calum MattocksChris Riddoch
Sep 14, 2007·International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity·Calum MattocksChris Riddoch
Feb 13, 2008·Annales D'urologie·R de Petriconi
Nov 5, 2008·British Journal of Sports Medicine·M Martyn-St James, S Carroll
Apr 8, 2010·European Journal of Applied Physiology·Diego Moliner-UrdialesJonatan R Ruiz
May 13, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·N C HarveyUNKNOWN SWS Study Group
Jul 1, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B Dawson-HughesL J Melton

❮ Previous
Next ❯

Citations

Oct 26, 2012·International Journal of Epidemiology·Jane E Ferrie
Jul 18, 2012·The Journal of Clinical Endocrinology and Metabolism·K DeereJ H Tobias
Jul 17, 2015·American Journal of Human Biology : the Official Journal of the Human Biology Council·Kimberly D WilliamsBradford Towne
Dec 30, 2015·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Alex IrelandJon H Tobias
Aug 11, 2016·American Journal of Human Biology : the Official Journal of the Human Biology Council·María Correa-RodríguezJacqueline Schmidt-RioValle
Feb 10, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Alex IrelandRachel Cooper
Oct 14, 2017·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ahmed ElhakeemJon H Tobias
Nov 18, 2017·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T ChristoffersenL A Ahmed
Aug 18, 2020·JAMA Network Open·Ahmed ElhakeemDeborah A Lawlor
Aug 14, 2020·International Journal of Environmental Research and Public Health·Stanislava StranavskaJaroslava Kopcakova
Mar 30, 2021·JBMR Plus·Alessandra CarrieroSandra J Shefelbine
Jan 9, 2020·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J M GenkingerS A Smith-Warner

❮ Previous
Next ❯

Software Mentioned

Actigraph
STATA
Newtest

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.