High incidence of Alloiococcus otitidis in children with otitis media, despite treatment with antibiotics

Journal of Clinical Microbiology
Atsushi HarimayaT Himi

Abstract

Acute otitis media (AOM) and otitis media with effusion (OME) are common diseases in childhood. Alloiococcus otitidis is a newly recognized species of gram-positive bacterium which was recently discovered as a pathogen associated with OME. Although some studies show that A. otitidis is frequently detected in children with OME, no study is available concerning the clinical efficiency of antibiotics against this organism. The prevalence of A. otitidis in 116 middle ear effusion specimens from 36 AOM and 52 OME patients was examined by culture and PCR. In addition, the prevalence of the bacterium was retrospectively investigated in relation to antibiotic use. A. otitidis was detected in 20 (50%) AOM and 47 (61%) OME specimens. The organism was the most frequent bacterium in AOM as well as in OME and was highly detected even in patients who had been treated with antibiotics, such as beta-lactams or erythromycin. The incidence of A. otitidis in our study was higher than that in Western countries, and our results suggest that drug-resistant strains of A. otitidis may be frequently spread in Japanese children. Our study suggests that antibiotics such as beta-lactams or erythromycin may not be sufficiently effective to eliminate this o...Continue Reading

References

Jan 1, 1992·International Journal of Systematic Bacteriology·M Aguirre, M D Collins
Aug 1, 1992·The Pediatric Infectious Disease Journal·C D BluestoneL M Martin
Jan 1, 1989·The Pediatric Infectious Disease Journal·G S Giebink
Jun 10, 1982·The New England Journal of Medicine·C D Bluestone
May 24, 1995·JAMA : the Journal of the American Medical Association·J C PostG D Ehrlich
Nov 1, 1995·Journal of Clinical Microbiology·G S BosleyD F Talkington
Nov 14, 1997·Journal of Clinical Microbiology·P H HendolinJ J Wahlfors
Feb 5, 1998·JAMA : the Journal of the American Medical Association·M G RaynerG D Ehrlich
Apr 7, 1999·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C Gómez-HernandoM Baquero
Oct 26, 1999·The Pediatric Infectious Disease Journal·P H HendolinJ Ylikoski
Oct 29, 2000·The Annals of Otology, Rhinology, and Laryngology·J TarkkanenP S Mattila
Oct 5, 2002·International Journal of Pediatric Otorhinolaryngology·Kimmo LeskinenJussi Jero
Dec 23, 2003·International Journal of Pediatric Otorhinolaryngology·Kimmo LeskinenJussi Jero
Nov 29, 2005·International Journal of Pediatric Otorhinolaryngology·Atsushi HarimayaTetsuo Himi

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Citations

Sep 4, 2013·Journal of Infection and Public Health·Mustafa CakarTurgay Celik
Feb 3, 2009·International Journal of Pediatric Otorhinolaryngology·Atsushi HarimayaTetsuo Himi
Jul 9, 2011·Scandinavian Journal of Infectious Diseases·Thomas NeumarkAnnika Törngren
Jan 5, 2011·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Junji MatsuoHiroyuki Yamaguchi
Nov 11, 2006·FEMS Immunology and Medical Microbiology·Atsushi HarimayaNobuhiro Fujii
Aug 2, 2007·FEMS Immunology and Medical Microbiology·Christopher Ashhurst-SmithC Caroline Blackwell
Jun 24, 2016·The Laryngoscope·Chun Ling ChanAlkis James Psaltis
Aug 25, 2016·European Annals of Otorhinolaryngology, Head and Neck Diseases·A MarhicM François
Jun 14, 2006·Diagnostic Microbiology and Infectious Disease·Robert SlingerShawn D Aaron
Jul 15, 2016·Journal of Clinical Microbiology·Saara SillanpääOndrej Cinek
Aug 2, 2017·MSystems·Ashley A RossJosh D Neufeld
Apr 18, 2008·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Isabel de Miguel Martinez, Angel Ramos Macias
May 1, 2020·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Izabela Korona-GlowniakAnna Malm
Oct 23, 2019·Frontiers in Cellular and Infection Microbiology·Allison R KolbeMarcos Pérez-Losada
Mar 3, 2020·Frontiers in Cellular and Infection Microbiology·Rachael LappanChristopher S Peacock
Nov 4, 2009·The Medical Journal of Australia·Peter S MorrisHarvey L C Coates
Jun 25, 2021·Journal of Medical Microbiology·Matthew Flynn, James Dooley

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