High incidence of aplastic anemia is linked with lower socioeconomic status of Indian population

Journal of Public Health
Pankaj MalhotraSubhash Varma

Abstract

The incidence of aplastic anemia (AA) is common in Asia than in western countries. In a case-control study conducted at a tertiary care hematology center in northern India, 102 patients of AA and 201 controls of other blood disorders (OBD) were included. Sociodemographic data and exposure to drugs, toxins and radiation were collected from the study population using a standard questionnaire. Socioeconomic status (SES) was classified based on a calculated standard of living (SL) score. Univariate and multivariate analyses were carried out to delineate the factors associated with incidence of AA. Patients with AA were significantly younger than those in control groups (mean age 27.5 ± 12.3 years, P < 0.01). The mean SL score was significantly lower in AA group (26.76 ± 12.88, P < 0.01) than in the controls. The mean monthly family income was significantly lower in AA group than in the controls (83.3% with monthly income <8000 INR, P < 0.01). On univariate analysis, AA group with lower SL score had >3 times higher odds of having the disease (odds ratio 3.41, 95% confidence interval 1.72-6.79, P < 0.0001) compared with the controls. On multivariate analysis, young age and low SES were found to be significantly associated with AA. Lo...Continue Reading

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Citations

Oct 4, 2016·Zeitschrift für Gesundheitswissenschaften = Journal of public health·Mehwesh TajTahir Sultan Shamsi
Feb 9, 2018·Hematology·Harshit KhuranaGaurav Prakash
Jan 8, 2020·Hematology·Parvez AhmedRaheel Iftikhar
Feb 15, 2017·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Prakas Kumar MandalPrantar Chakrabarti
Oct 28, 2017·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Gaurav PrakashPankaj Malhotra
May 16, 2021·Transfusion·Joy John MammenShobini Rajan

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