Abstract
Vulvar carcinoma is mainly treated surgically and has an overall good prognosis. Despite the development of minimally invasive surgical procedures in recent years, morbidity remains significant. The aim of the study was to determine the incidence and risk factors of erysipelas after surgical treatment for vulvar carcinoma. This retrospective observational study was performed within the Comprehensive Cancer Centre South. The study included patients (N = 116) who underwent surgery for primary vulvar carcinoma between 2005 and 2012. Patients with International Federation of Gynecology and Obstetrics stage IA and IV were excluded. Clinical and histopathological data were analyzed using logistic regression, χ(2) tests, Fisher exact tests, independent t tests, and nonparametric tests. Primary outcome was the incidence of postoperative erysipelas and determination of risk factors for erysipelas. Secondary outcome included other comorbidities. A total of 23 patients (20%) with vulvar carcinoma had 1 or more episodes of erysipelas. The risk of developing erysipelas was significantly higher in patients who underwent lymph node dissection than in those who underwent sentinel node biopsy (36% [n = 12] and 14% [n = 11], respectively, P = 0....Continue Reading
References
Jun 1, 1995·Gynecologic Oncology·M P BurgerJ Bouma
Apr 29, 2000·Gynecologic Oncology·J G BellG C Reid
Nov 14, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A LeminenJ Paavonen
Sep 5, 2001·Gynecologic Oncology·N GouldR Mannel
Nov 19, 2002·Cancer·Joanne A De HulluAte G J Van Der Zee
Mar 22, 2003·Journal of the American College of Surgeons·Roman RouzierBernard-Jean Paniel
Aug 13, 2003·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·K N GaarenstroomI Vergote
Sep 6, 2003·International Journal of Radiation Oncology, Biology, Physics·Angela KatzCharles F Levenback
Apr 1, 1960·The Journal of Obstetrics and Gynaecology of the British Empire·L M NORBURN, R B COLES
Feb 19, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ate G J Van der ZeeWim J Sluiter
May 17, 2008·Gynecologic Oncology·Jay W CarlsonUNKNOWN Gynecologic Oncology Group
Jan 2, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Hedwig P van de NieuwenhofJoanne A de Hullu
Mar 20, 2009·Gynecologic Oncology·M H M OonkA G J van der Zee
Apr 16, 2009·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Sergio Pecorelli
Sep 5, 2009·The American Journal of Surgical Pathology·Donald L WeaverDavid N Krag
Jun 12, 2010·The Lancet Oncology·Maaike H OonkAte G van der Zee
Jul 8, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Saskia M A GroenenCurt W Burger
Aug 6, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Beate SennManuela Eicher
Oct 6, 2011·British Journal of Cancer·F HintenJ A de Hullu