High incidence of late infective endocarditis in bovine jugular vein valved conduits

The Journal of Thoracic and Cardiovascular Surgery
Ziv BeckermanCharles D Fraser

Abstract

Bovine jugular vein (BJV) grafts (Medtronic, Inc, Minneapolis, Minn) are used to restore right ventricle-to-pulmonary artery continuity. Recent studies have associated these grafts with the development of infective endocarditis. The purpose of this study was to report the incidence of endocarditis in BJV grafts. All BJV grafts placed in the right ventricle-to-pulmonary artery position between 2001 and 2017 at our institution were included. Freedom from endocarditis was analyzed using the Kaplan-Meier method and parametric survival regression models. Overall, 228 patients underwent placement of 253 BJV grafts. The median duration of conduit follow-up was 6 years (5 months to 14 years). Twenty-five conduits developed endocarditis, yielding an incidence of 10% at a median of 7.5 years after surgery. Median duration of symptoms before the diagnosis of endocarditis was 21 days (3-180 days). The most common infectious agents were viridans streptococci (n = 13; 52%). Freedom from endocarditis at 5 and 10 years was 97% and 77%, respectively. After controlling for confounders, BJV grafts had a higher incidence of endocarditis compared with homografts (P < .001). Twenty-three (92%) of the conduits that developed endocarditis were managed...Continue Reading

Citations

Dec 19, 2019·Cardiology in the Young·Parth M PatelJohn W Brown
Jul 26, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Takako MiyazakiHitoshi Yaku
Jul 16, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jill Jussli-MelchersTim Attmann
Jul 26, 2018·Frontiers in Pediatrics·Gareth J Morgan
Jan 11, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Michael MegalySantiago Garcia
Mar 6, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Gregor GierlingerRudolf Mair
Mar 9, 2021·World Journal for Pediatric & Congenital Heart Surgery·Akshat SaxenaDavid S Winlaw
Mar 2, 2021·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Javid RajaBaiju Sasi Dharan
Mar 1, 2021·The Journal of Thoracic and Cardiovascular Surgery·Robert G WillettsPhil Botha
May 19, 2019·The Annals of Thoracic Surgery·Kwang Ho ChoiJoonyong Cho
Mar 18, 2021·Artificial Organs·Juyi WanWenbin Li
Jun 1, 2021·Journal of Cardiac Surgery·Filippo RapettoGianni D Angelini
Aug 15, 2021·Journal of Biomedical Materials Research. Part a·Irina Yu ZhuravlevaNatalia R Nichay
Oct 2, 2021·World Journal for Pediatric & Congenital Heart Surgery·Alqasem Fuad H Al MosaChristo Tchervenkov

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