High incidence of second basal cell skin cancers

International Journal of Cancer. Journal International Du Cancer
Fabio LeviCarlo La Vecchia

Abstract

We considered the risk of second basal cell cancers (BCC) of the skin using a population-based series of 1,868 BCC collected between 1976 and 1985 in the Swiss Cantons of Vaud and Neuchâtel, and followed-up to the end of 2003. Overall, 507 second BCC were observed versus 59.98 expected, corresponding to a standardized incidence ratio (SIR) of 8.45 (95% CI: 7.73-9.22). The SIRs were similar in men and women in subsequent calendar periods, but tended to decline with advancing age at diagnosis of first BCC, from 13.98 below age 50 to 7.13 at age 70 or over. Consequently, the rate of first BCC increased to approximately 30-fold between 7/100,000 at age 30-39 and 200/100,000 at age 70-79, but the rate of second BCC increased only about 3-fold between 31/1,000 at age 30-39 and 110/1,000 at age 70-79. The cumulative risk of second BCC was 11% at 5 years, 21% at 10 years and 40% at 20 years. This study indicates that the relative (but not the absolute) risk of second BCC is greater at younger age and declines with advancing age, and is therefore compatible with an excess baseline risk in a population of susceptible individuals.

References

Jan 2, 1988·British Medical Journal·G G GilesP Foley
Dec 15, 1988·International Journal of Cancer. Journal International Du Cancer·F LeviG Mezzanotte
Jan 1, 1982·Epidemiologic Reviews·J A Lee
Oct 1, 1995·British Journal of Cancer·F LeviC La Vecchia
Nov 28, 2000·International Journal of Cancer. Journal International Du Cancer·P Vaittinen, K Hemminki
Dec 2, 2000·Nature Genetics·D Easton
Jul 31, 2001·International Journal of Cancer. Journal International Du Cancer·F LeviC La Vecchia
Aug 16, 2001·Journal of the National Cancer Institute·I ShureiqiS M Lippman
Sep 6, 2001·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·F LeviC La Vecchia
Apr 4, 2002·Journal of the National Cancer Institute·Fabio LeviCarlo La Vecchia
Sep 18, 2004·The Journal of Investigative Dermatology·Esther de VriesJan Willem Coebergh
Jun 16, 2005·International Journal of Cancer. Journal International Du Cancer·Fabio LeviCarlo La Vecchia

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Citations

Oct 4, 2011·Indian Journal of Dermatology·Zahra HallajiMostafa Mirshams-Shahshahani
Apr 3, 2014·The Journal of Clinical Investigation·G Paolo Dotto
Aug 30, 2014·Annals of Epidemiology·Fabio LeviCarlo La Vecchia
Mar 4, 2009·Dermatologic Clinics·Luigi Naldi, Liliane Chatenoud
Jul 3, 2008·The British Journal of Dermatology·N R TelferUNKNOWN British Association of Dermatologists
Jul 21, 2007·International Journal of Cancer. Journal International Du Cancer·Fiona Bath-HextallRichard Hubbard
Apr 10, 2007·International Journal of Cancer. Journal International Du Cancer·Fabio LeviCarlo La Vecchia
Aug 21, 2012·International Journal of Cancer. Journal International Du Cancer·Fabio LeviCarlo La Vecchia
Oct 16, 2013·The British Journal of Dermatology·J J Domínguez-CruzD Moreno-Ramirez
Apr 24, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Sophie C FlohilTamar Nijsten
Jul 12, 2012·Archives of Plastic Surgery·Seum Chung
Oct 19, 2016·Head & Neck·Thomas J OwUNKNOWN Education Committee of the American Head and Neck Society (AHNS)
Aug 21, 2008·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Fabio LeviCarlo La Vecchia
Feb 22, 2017·Wiener medizinische Wochenschrift·Georgi TchernevUwe Wollina
Apr 1, 2014·Archives of Craniofacial Surgery·Joon Ho LeeTae Jung Jang
May 13, 2020·Oncology Reviews·Alena FurdovaJuraj Sekac
Apr 4, 2020·Actas dermo-sifiliográficas·F Vílchez-MárquezP Redondo-Bellón

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