High-intensity ultraendurance promotes early release of muscle injury markers

British Journal of Sports Medicine
Artur BessaL-C Cameron

Abstract

To evaluate the impact of high-intensity ultraendurance (HIU) cycling, using it as a possible way to understand muscle injury kinetics and blood immune cells' release during high-intensity prolonged exercise Male amateur triathletes enrolled during a cycling race of the International Bike Championship 800 km cycling relay (approximately 23 h). Each athlete alternately cycled 20-25 minutes until exhaustion and performed a total of approximately 200 km. Creatine kinase levels in blood reached a 300% rise in a sigmoidal pattern, while lactate dehydrogenase levels increased by 30-40% following a hyperbolic pattern. Aspartate aminotransferase and alanine aminotransferase levels increased by up to 250% and 140%, respectively. Liver injury markers such as alkaline phosphatase and gamma-glutamyltransferase remained stable. Platelets increased by 20-30% from pre-exercise, and there was no change in haematocrit during the race. White blood cells rose by nearly 200%. Leucocytes rose 210% during the race, with a major component coming from neutrophils, which increased more than 300%. Triacylglycerol levels were decreased at the finish and total cholesterol levels remained unchanged. Urate increased (by up to 35%) during the first half of t...Continue Reading

Citations

Sep 1, 2011·European Journal of Applied Physiology·Zbigniew WaśkiewiczDagmara Gerasimuk
Sep 17, 2011·European Journal of Applied Physiology·David S RowlandsM A Tarnopolsky
Sep 5, 2013·European Journal of Applied Physiology·Barbara KłapcińskaJózef Langfort
Jul 3, 2010·The British Journal of Nutrition·Rosemeire Dantas de AlmeidaLuiz-Claudio Cameron
Nov 21, 2013·European Journal of Sport Science·Moisés de HoyoMaria Del Carmen Escobar
Oct 8, 2011·Omics : a Journal of Integrative Biology·Nathália Maria ResendeL C Cameron
Apr 17, 2013·Journal of the International Society of Sports Nutrition·Seung-Lyul OhWook Song
Jun 28, 2012·Journal of the International Society of Sports Nutrition·Luis Carlos GonçalvesLuiz-Claudio Cameron
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