High intramuscular adipose tissue content as a precondition of sarcopenia in patients with aortic aneurysm

Surgery Today
Yutaka MatsubaraYoshihiko Maehara

Abstract

Sarcopenia is a major problem of the elderly. Although little is known about the cause of sarcopenia, the intramuscular adipose tissue content (IMAC) is known to be a cause of sarcopenia. The aim of this study was to investigate the significance of IMAC as a cause of sarcopenia. We evaluated patients who underwent aneurysm repair and were monitored preoperatively and 3 years postoperatively by computed tomography (CT). The skeletal muscle area and IMAC were measured on preoperative L3 CT images. The clinical characteristics and risk factors for skeletal muscle wasting were assessed. Among the 155 patients, 38 (24.5%) had > 10% skeletal muscle wasting 3 years after the operation. Patients with > 10% skeletal muscle wasting had higher IMACs of the iliopsoas (- 0.31 ± 0.01 vs. -0.45 ± 0.01, P < 0.001) muscles and higher rates of cerebrovascular infarctions (7.7 vs. 23.7%, P = 0.0068), lung cancer (0 vs. 10.5%, P < 0.001), and urgent operations (0.9 vs. 10.5%, P = 0.029) and a longer postoperative fasting period (1.3 ± 0.1 vs. 3.1 ± 0.9 days, P < 0.001) than those without > 10% skeletal muscle wasting. The IMAC of the iliopsoas muscle correlated strongly with skeletal muscle wasting (P < 0.05, r = 0.70). A high IMAC of the iliopsoa...Continue Reading

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Citations

Aug 18, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Hiroki FukuharaYoshihiko Watarai
Jul 16, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Mahmoud MacshutShinji Uemoto
Sep 20, 2020·Annals of Vascular Surgery·Vânia Constâncio OliveiraManuel Fonseca

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