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High LDL levels lessen bone destruction during antigen-induced arthritis by inhibiting osteoclast formation and function

Bone

Jan 9, 2020

Giuliana AsconePeter L E M van Lent

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Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by severe joint inflammation and bone destruction as the result of increased numbers and activity of osteoclasts. RA is often associated with metabolic syndrome, whereby elevated levels of LDL are oxidized into o...read more

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Antigens
Arthritis
Rheumatoid Arthritis
Biological Markers
Bone Marrow
Inflammation
Joints
Low-Density Lipoproteins
Metabolism
Laboratory mice
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High LDL levels lessen bone destruction during antigen-induced arthritis by inhibiting osteoclast formation and function

Bone

Jan 9, 2020

Giuliana AsconePeter L E M van Lent

PMID: 31712132

DOI: 10.1016/j.bone.2019.115140

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by severe joint inflammation and bone destruction as the result of increased numbers and activity of osteoclasts. RA is often associated with metabolic syndrome, whereby elevated levels of LDL are oxidized into o...read more

Mentioned in this Paper

Antigens
Arthritis
Rheumatoid Arthritis
Biological Markers
Bone Marrow

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