High-level association of bovine digital dermatitis Treponema spp. with contagious ovine digital dermatitis lesions and presence of Fusobacterium necrophorum and Dichelobacter nodosus

Journal of Clinical Microbiology
L E SullivanNicholas J Evans

Abstract

Contagious ovine digital dermatitis (CODD) is an important foot disease in sheep, with significant animal welfare and economic implications. It is thought that CODD emerged from bovine digital dermatitis (BDD) via treponemal bacteria. With wildlife species such as elk now suffering a CODD-like disease, it is imperative to clarify these disease etiologies. A large investigation into treponemal association with CODD is warranted. CODD lesions (n = 58) and healthy sheep foot tissues (n = 56) were analyzed by PCR for the three BDD-associated Treponema phylogroups and two other lameness-associated bacteria, Dichelobacter nodosus and Fusobacterium necrophorum. Spirochete culture was also attempted on CODD lesions. "Treponema medium/Treponema vincentii-like," "Treponema phagedenis-like," and Treponema pedis spirochetes were identified in 39/58 (67%), 49/58 (85%), and 41/58 (71%) of CODD lesions, respectively. One or more BDD-associated Treponema phylogroups were detected in 100% of CODD lesions. Healthy foot tissues did not amplify BDD-associated Treponema phylogroup DNA. D. nodosus and F. necrophorum were present in 34/58 (59%) and 41/58 (71%) of CODD lesions and 22/56 (39%) and 5/56 (9%) of healthy foot tissues, respectively. Thirty...Continue Reading

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Citations

Feb 7, 2016·Research in Veterinary Science·Simon R CleggNicholas J Evans
Nov 10, 2015·Microbial Pathogenesis·Wenling GaoRory M Watt
May 11, 2016·Journal of Comparative Pathology·H E Crosby-DurraniJ S Duncan
Jun 19, 2016·The Veterinary Record·G MaboniS Tötemeyer
Sep 15, 2019·Tropical Animal Health and Production·Nader Maher SobhyAshraf Awad
Jan 23, 2016·Veterinary Dermatology·Simon R CleggNicholas J Evans
Aug 3, 2019·Animals : an Open Access Journal From MDPI·Athanasios I GelasakisIoannis Bossis
Aug 29, 2020·Acta Veterinaria Scandinavica·Philip Christian TegtmeyerMartin Ganter
Aug 18, 2021·Acta Veterinaria Scandinavica·Malin BernhardUlrika König
Oct 12, 2021·Frontiers in Veterinary Science·Gareth J StatonJennifer S Duncan

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