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High levels of genetically-intact HIV in HLA-DR+ memory T-cells indicates their value for reservoir studies

AIDS

Jan 9, 2020

Bethany A HorsburghSarah Palmer

Abstract

The contribution of HLA-DR+ memory CD4+ T-cells to the HIV reservoir during prolonged antiretroviral therapy is unclear as these cells are commonly excluded when assessing for replication-competent HIV. To address this issue, we examined the distribution of genetically intact HIV DNA wi...read more

Mentioned in this Paper

Rostrotemporal Auditory Area
DNA, Viral
Cell Proliferation
DNA Replication
Nucleic Acid Sequencing
Intracellular
CD4 Positive T Lymphocytes
Genome
Landscapes
HLA-DR Antigens
5
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High levels of genetically-intact HIV in HLA-DR+ memory T-cells indicates their value for reservoir studies

AIDS

Jan 9, 2020

Bethany A HorsburghSarah Palmer

PMID: 31913161

DOI: 10.1097/qad.0000000000002465

Abstract

The contribution of HLA-DR+ memory CD4+ T-cells to the HIV reservoir during prolonged antiretroviral therapy is unclear as these cells are commonly excluded when assessing for replication-competent HIV. To address this issue, we examined the distribution of genetically intact HIV DNA wi...read more

Mentioned in this Paper

Rostrotemporal Auditory Area
DNA, Viral
Cell Proliferation
DNA Replication
Nucleic Acid Sequencing
Intracellular
CD4 Positive T Lymphocytes
Genome
Landscapes
HLA-DR Antigens
5

Similar Papers Found In These Feeds

National Institute of Allergy & Infectious Diseases (NIAID)

National Institute of Allergy and Infectious Diseases (NIAID) goal is to perform leading research to understand, treat, and prevent infectious, immunologic, and allergic diseases. Follow this feed to stay updated on research from this group.

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