High Levels of Psychological Resilience Associated With Less Disease Activity, Better Quality of Life, and Fewer Surgeries in Inflammatory Bowel Disease.

Inflammatory Bowel Diseases
Priya SehgalLaurie Keefer

Abstract

Stress and depression are risk factors for inflammatory bowel disease (IBD) exacerbations. It is unknown if resilience, or one's ability to recover from adversity, impacts disease course. The aim of this study was to examine the association between resilience and IBD disease activity, quality of life (QoL), and IBD-related surgeries. We performed a cross-sectional study of IBD patients at an academic center. Patients completed the Connor-Davidson Resilience Scale questionnaire, which measures resilience (high resilience score ≥ 35). The primary outcome was IBD disease activity, measured by Mayo score and Harvey-Bradshaw Index (HBI). The QoL and IBD-related surgeries were also assessed. Multivariate linear regression was conducted to assess the association of high resilience with disease activity and QoL. Our patient sample comprised 92 patients with ulcerative colitis (UC) and 137 patients with Crohn disease (CD). High resilience was noted in 27% of patients with UC and 21.5% of patients with CD. Among patients with UC, those with high resilience had a mean Mayo score of 1.54, and those with low resilience had a mean Mayo score of 4.31, P < 0.001. Among patients with CD, those with high resilience had a mean HBI of 2.31, and th...Continue Reading

References

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Mar 7, 2019·Inflammatory Bowel Diseases·Tiffany H TaftStephen B Hanauer

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Citations

Mar 16, 2021·The Lancet. Gastroenterology & Hepatology·Laurie Keefer
Jun 17, 2021·Expert Review of Gastroenterology & Hepatology·Marla C DubinskyLaurie Keefer
Aug 3, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Tiffany H TaftLinda Nguyen
Aug 28, 2021·Inflammatory Bowel Diseases·Alicia PhilippouLaurie Keefer

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