High mortality impact of Staphylococcus argenteus on patients with community-onset staphylococcal bacteraemia

International Journal of Antimicrobial Agents
Shey-Ying ChenPo-Ren Hsueh

Abstract

Staphylococcus argenteus is increasingly reported. Evaluating the impact of S. argenteus infection on patient outcomes for future therapeutic and infection control decision-making is imperative. A retrospective study was conducted to investigate the prevalence of S. argenteus bacteraemia at a Taiwanese medical centre between 2010-2012. Staphylococcus argenteus was identified based on absence of the crtM gene and multilocus sequence typing (MLST) analysis. Clinical characteristics between S. argenteus and Staphylococcus aureus bacteraemia were compared. The independent effect of S. argenteus on bacteraemia mortality was evaluated. A total of 47 S. argenteus isolates were re-identified from 394 S. aureus bacteraemia isolates. All S. argenteus isolates were susceptible to methicillin and multiple other antibiotics. Most of the S. argenteus isolates (36/47; 76.6%) were sequence type 2550 (ST2550). Comparing the 47 S. argenteus bacteraemia cases with 232 methicillin-susceptible S. aureus (MSSA) bacteraemia cases, S. argenteus bacteraemia patients had significantly higher percentages of polymicrobial infection, recent hospitalisation in the past 3 months, thrombocytopenia, lower respiratory tract infection and short-term mortality. C...Continue Reading

Citations

Jan 8, 2020·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Abiola SenokRalf Ehricht
Jun 24, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Farah AlhusseinCihan Papan
Jul 29, 2020·Antimicrobial Agents and Chemotherapy·Arnold S Bayer, Steven Y C Tong
Feb 26, 2021·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Leonie E A BankRoel H T Nijhuis
Aug 9, 2019·Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan·Yasunori Suzuki
Dec 7, 2021·Frontiers in Microbiology·Shi WuQingping Wu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.