High-performance digital image analyzer for quantitative autoradiography

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
J L LearR Muth

Abstract

A digital image-processing system was developed for high-spatial resolution analysis of autoradiograms. The system uses a linear array of charge-coupled devices operating under computer control to scan and digitize autoradiograms into 512 X 512 matrices with 256 gray levels. Software was developed to facilitate quantitative analysis of autoradiograms produced in single- and multiple-tracer studies. Because of the high output, linearity, and accuracy of the solid-state detectors, the system was found to digitize autoradiograms significantly more precisely and accurately than previously described video camera- or photomultiplier tube-based scanning densitometers.

References

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Citations

Jun 1, 1994·Annals of Neurology·A HandforthD M Treiman
Jun 1, 1989·Metabolic Brain Disease·J L Lear, R F Ackermann
May 1, 1988·Journal of Neuroscience Methods·S C Jones, D F Lu
Aug 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·M KadekaroL Sokoloff
Aug 10, 2000·Neoplasia : an International Journal for Oncology Research·S S GambhirR Blasberg
Dec 1, 1989·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R F Ackermann, J L Lear
Aug 1, 1988·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·J L Lear, R F Ackermann
Aug 1, 1988·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·J L Lear
Aug 1, 1989·Stroke; a Journal of Cerebral Circulation·R H BradleyG Hillman

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