High-Performance Graphene-Fiber-Based Neural Recording Microelectrodes

Advanced Materials
Kezhong WangGordon Wallace

Abstract

Fabrication of flexible and free-standing graphene-fiber- (GF-) based microelectrode arrays with a thin platinum coating, acting as a current collector, results in a structure with low impedance, high surface area, and excellent electrochemical properties. This modification results in a strong synergistic effect between these two constituents leading to a robust and superior hybrid material with better performance than either graphene electrodes or Pt electrodes. The low impedance and porous structure of the GF results in an unrivalled charge injection capacity of 10.34 mC cm-2 with the ability to record and detect neuronal activity. Furthermore, the thin Pt layer transfers the collected signals along the microelectrode efficiently. In vivo studies show that microelectrodes implanted in the rat cerebral cortex can detect neuronal activity with remarkably high signal-to-noise ratio (SNR) of 9.2 dB in an area as small as an individual neuron.

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Citations

Jul 25, 2019·Advanced Materials·Tong XuLiangti Qu
May 7, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Chengqiang TangHuisheng Peng
Jul 17, 2020·Chemical Society Reviews·Yin FangBozhi Tian
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Aug 11, 2020·Advanced Science·Minghui DuShifeng Zhou
Aug 14, 2019·Advanced Materials·Bo FangChao Gao
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Jul 31, 2020·Biosensors & Bioelectronics·Valentin SaunierAli Maziz
May 21, 2021·Advanced Materials·Yo Han ChoJang-Ung Park
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Dec 5, 2019·ACS Applied Materials & Interfaces·Huibin QingFeng Xu
Aug 26, 2021·ACS Nano·Yingqiao WangTzahi Cohen-Karni
May 15, 2020·Analytical Chemistry·Pankaj GuptaNoe T Alvarez
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Aug 18, 2021·Journal of Neural Engineering·Mamta DeviSwati Sharma
Sep 19, 2021·Communications Biology·Maria A Gonzalez-GonzalezMario Romero-Ortega
Nov 20, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Boyu XuXiao-Dong Zhang
Dec 14, 2021·Frontiers in Bioengineering and Biotechnology·Venkata Suresh VajralaAli Maziz
Dec 29, 2021·Chemical Reviews·Kyoung Won ChoDae-Hyeong Kim

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