PMID: 2114217Jun 1, 1990Paper

High-performance liquid chromatographic analysis of monoamines and some of their gamma-glutamyl conjugates produced by the brain and other tissues of Helix aspersa (Gastropoda)

Cellular and Molecular Neurobiology
B D SloleyD A Durden

Abstract

1. Earlier reports from this and other laboratories have indicated that wide variations exist in estimates of the concentrations of norepinephrine in the brain and heart of the snail Helix aspersa. This is a report on investigations of norepinephrine concentrations in Helix aspersa tissues using high-performance liquid chromatography with electrochemical detection. In addition, the effects of treatment with some amino acid precursors or enzyme inhibitors on the concentrations of norepinephrine, dopamine, 5-hydroxytryptamine, and some of their metabolites were investigated. 2. The levels of norepinephrine in the brain were low (46 ng/g) in comparison to dopamine (2.1) micrograms/g) and 5-hydroxytryptamine (2.6 micrograms/g). Epinephrine was not observed in either snail heart of snail nervous tissue. 3. Administration of L-3,4-dihydroxyphenylalanine resulted in elevated snail brain dopamine, while 3,4-dihydroxyphenylserine treatment increased norepinephrine. Treatment with blockers of tyrosine hydroxylase and aromatic-L-amino acid decarboxylase reduced dopamine concentrations without affecting 5-hydroxytryptamine. 4. The dopamine metabolite 3,4-dihydroxyphenylacetic acid was observed only after administration of L-3,4-dihydroxyph...Continue Reading

References

Jun 1, 1975·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·M Wollemann, K S Rózsa
Nov 4, 1977·Brain Research·J E Goldman, J H Schwartz
Jul 15, 1975·Experientia·P B GuthrieN N Osborne
Oct 1, 1988·Journal of Neurochemistry·B A BattelleA C Wishart
Nov 11, 1985·Brain Research·A FranchiniE Caselgrandi
Sep 1, 1972·Comparative and General Pharmacology·A V Juorio, S W Killick
May 1, 1974·Canadian Journal of Biochemistry·S R PhilipsA A Boulton
Mar 1, 1970·Comparative and General Pharmacology·N N Osborne, G A Cottrell
Jan 1, 1984·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·B D Sloley, R G Downer
Jan 1, 1984·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·H Straub, D Kuhlmann
Oct 1, 1961·Comparative Biochemistry and Physiology·G A KERKUT, R J WALKER

❮ Previous
Next ❯

Citations

Mar 22, 2013·Invertebrate Neuroscience : in·T D Mayorova, I A Kosevich
Jan 1, 1996·Insect Biochemistry and Molecular Biology·R Kaufman, D Sloley
May 5, 2004·Fish & Shellfish Immunology·Asunción CaoRamiro Barcia
Jun 7, 2000·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·V Santhanagopalan, T P Yoshino
Aug 6, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Barbara-Anne Battelle, Mary K Hart
Apr 6, 2007·Zhurnal evoliutsionnoĭ biokhimii i fiziologii·V G SolomonovaP V Avdonin
Apr 24, 2001·General and Comparative Endocrinology·A LacosteS A Poulet
Jun 9, 2009·Journal of Biotechnology·Isvett Josefina Flores-SanchezRobert Verpoorte
May 18, 2016·The Journal of Comparative Neurology·Ryota MatsuoYuko Matsuo
Apr 20, 2019·Frontiers in Behavioral Neuroscience·Yuki TotaniEtsuro Ito
Aug 23, 2020·General and Comparative Endocrinology·Rebecca J WilsonThomas C Jones
Jul 9, 2011·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Sodikdjon A Kodirov

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.