PMID: 6413677Aug 1, 1983Paper

High-performance liquid chromatographic determination of nitroglycerin in sublingual, sustained-release, and ointment dosage forms

Journal of Pharmaceutical Sciences
C S Olsen, H S Scroggins

Abstract

A rapid, precise, sensitive, and specific assay for nitroglycerin in sublingual, sustained-release, and ointment dosage forms using high-performance liquid chromatography is described. The nitroglycerin dosage forms were dissolved in methanol, filtered, and injected directly into the liquid chromatograph. A variable-wavelength UV detector operated at 220 nm and a C18 microporous silica column were employed. The mobile phase was methanol-water (40:60).

References

Jan 1, 1969·Journal of Pharmaceutical Sciences·B C Flann

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Citations

Nov 1, 1988·The American Journal of Emergency Medicine·S J RottmanS H Curry
Jul 1, 1985·Biopharmaceutics & Drug Disposition·S H Curry, S M Aburawi

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