High-power and short-duration ablation for pulmonary vein isolation: Safety, efficacy, and long-term durability

Journal of Cardiovascular Electrophysiology
Michael BarkaganElad Anter

Abstract

PV reconnection is often the result of catheter instability and tissue edema. High-power short-duration (HP-SD) ablation strategies have been shown to improve atrial linear continuity in acute pre-clinical models. This study compares the safety, efficacy, and long-term durability of HP-SD ablation with conventional ablation. In 6 swine, 2 ablation lines were performed anterior and posterior to the crista terminalis, in the smooth and trabeculated right atrium, respectively; and the right superior PV was isolated. In 3 swine, ablation was performed using conventional parameters (Thermocool-Smarttouch® SF; 30 W/30 seconds) and in 3 other swine using HP-SD parameters (QDOT-MICRO™, 90 W/4 seconds). After 30 days, linear integrity was examined by voltage mapping and pacing, and the heart and surrounding tissues were examined by histopathology. Acute line integrity was achieved with both ablation strategies; however, HP-SD ablation required 80% less RF time compared with conventional ablation (P ≤ 0.01 for all lines). Chronic line integrity was higher with HP-SD ablation: all 3 posterior lines were continuous and transmural compared to only 1 line created by conventional ablation. In the trabeculated tissue, HP-SD ablation lesions we...Continue Reading

Associated Clinical Trials

Mar 6, 2020·Antonio Berruezo, MD, PhD

References

Feb 18, 2014·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Elad AnterMark E Josephson
Mar 4, 2014·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Elad AnterMark E Josephson
Jun 5, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Josef KautznerKarl-Heinz Kuck
Oct 13, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Hamid GhanbariAman Chugh
May 14, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Waqas UllahUNKNOWN UK Multicentre Trials Group**
Apr 30, 2017·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Eran LeshemElad Anter
Aug 2, 2018·JACC. Clinical Electrophysiology·Eran LeshemElad Anter

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Citations

Jun 30, 2018·Journal of Cardiovascular Electrophysiology·Felix Bourier, Pierre Jais
Jun 6, 2019·Circulation. Arrhythmia and Electrophysiology·William H Sauer, Wendy S Tzou
Jul 30, 2019·Journal of Cardiovascular Electrophysiology·Daniel GelmanMaria Drangova
Nov 13, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Sergio Castrejón-CastrejónJosé Luis Merino
Mar 10, 2020·Journal of Cardiovascular Electrophysiology·Maria KyriakopoulouSebastien Knecht
Jul 6, 2020·Journal of Cardiovascular Electrophysiology·Jie QiuGuangzhi Chen
Jul 23, 2020·Pacing and Clinical Electrophysiology : PACE·Hee-Jin KwonYoung Keun On
Aug 19, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Dong Geum ShinHong Euy Lim
Feb 26, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Clemens Jilek, Waqas Ullah
Dec 25, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Marc KottmaierIsabel Deisenhofer
Feb 6, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Thomas DenekeHelmut Pürerfellner
Jul 21, 2020·Arrhythmia & Electrophysiology Review·Irum D KotadiaMark O'Neill
Oct 19, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Tom De PotterPeter Geelen
Dec 1, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Mohammadali HabibiHugh Calkins
Jan 1, 2021·Journal of Cardiovascular Electrophysiology·Roger A Winkle
Dec 11, 2020·Circulation. Arrhythmia and Electrophysiology·Jean-Yves WielandtsSebastien Knecht
Jan 22, 2021·Journal of Cardiovascular Electrophysiology·Felix BourierMélèze Hocini
Oct 23, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Thomas J BuistArif Elvan
Feb 2, 2021·Korean Circulation Journal·Dong Geum Shin, Hong Euy Lim
Nov 7, 2020·Journal of Cardiovascular Electrophysiology·Jakrin KewcharoenLeenhapong Navaravong
Oct 15, 2020·Nature Reviews. Cardiology·Ramanathan ParameswaranJonathan M Kalman
Mar 17, 2021·Journal of Cardiovascular Electrophysiology·Gustavo S Guandalini, Francis E Marchlinski
Apr 14, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Sergi Coderch-NavarroAna González-Suárez
Apr 23, 2021·Expert Review of Medical Devices·Weyland ChengPenggao Wang
May 13, 2021·Future Cardiology·Jean-Yves WielandtsSébastien Knecht
Jul 20, 2019·JACC. Clinical Electrophysiology·Vivek Y ReddyHelmut Pürerfellner
Sep 10, 2021·Pacing and Clinical Electrophysiology : PACE·Giuseppe StabileFrancesco Solimene

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