High-power, Short-duration Radiofrequency Ablation for the Treatment of AF

Arrhythmia & Electrophysiology Review
Irum D KotadiaMark O'Neill

Abstract

High-power, short-duration (HPSD) ablation for the treatment of AF is emerging as an alternative to ablation using conventional ablation generator settings characterised by lower power and longer duration. Although the reported potential advantages of HPSD ablation include less tissue oedema and collateral tissue damage, a reduction in procedural time and superior ablation lesion formation, clinical studies of HPSD ablation validating these observations are limited. One of the main challenges for HPSD ablation has been the inability to adequately assess temperature and lesion formation in real time. Novel catheter designs may improve the accuracy of intra-ablation temperature recording and correspondingly may improve the safety profile of HPSD ablation. Clinical studies of HPSD ablation are on-going and interpretation of the data from these and other studies will be required to ascertain the clinical value of HPSD ablation.

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Citations

Aug 8, 2020·Journal of Cardiovascular Electrophysiology·Mark D O'Neill, Steven E Williams
Jan 24, 2021·Journal of Cardiovascular Electrophysiology·Oluwaseun AdeolaGregory Michaud
Aug 2, 2021·Progress in Cardiovascular Diseases·Robert J Knotts, Chirag R Barbhaiya
Sep 15, 2021·Current Opinion in Cardiology·Thomas Flautt, Miguel Valderrábano

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NCT03775512

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