High-power short-duration versus standard radiofrequency ablation: Insights on lesion metrics

Journal of Cardiovascular Electrophysiology
Felix BourierPierre Jais

Abstract

Radiofrequency (RF) lesion metrics are influenced by underlying parameters like RF power, duration, and contact force (CF), and utilization of lesion metric indices (ablation index [AI]) is a proposed strategy to predict lesion quality. The aim of this study was to analyze the influence of underlying parameters on lesion metrics of high-power short-duration (HPSD) and standard RF applications using an in silico and ex vivo model. An in silico simulation study was designed to simulate HPSD and standard ablations, in which ablation parameters could systematically be varied. For each simulated ablation process (n = 5732), the corresponding AI value was calculated. HPSD and standard RF settings were then applied in a porcine ex vivo model ( n = 120 lesions). The resulting lesion metrics were compared and analyzed regarding underlying parameters. RF applications of 50 W/13 seconds, 60 W/10 seconds, 70 W/7 seconds, and 80 W/6 seconds resulted in lesion volumes not significantly different from standard RF applications (30 W/30 seconds, P > 0.05). HPSD lesion diameters were significantly larger and lesion depths were significantly smaller ( P < 0.01) when compared with standard settings. Prolonging RF duration from 5 to 10 seconds resu...Continue Reading

Associated Clinical Trials

Mar 6, 2020·Antonio Berruezo, MD, PhD

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Citations

Oct 26, 2018·Journal of Cardiovascular Electrophysiology·Parin J Patel, Benzy J Padanilam
Mar 27, 2019·Journal of Cardiovascular Electrophysiology·Tetsuma KawajiShinji Miki
Jun 22, 2019·Journal of Cardiovascular Electrophysiology·Takahiko NagaseKazuo Matsumoto
Aug 9, 2019·Journal of Cardiovascular Electrophysiology·Roger A Winkle
Nov 14, 2019·Herzschrittmachertherapie & Elektrophysiologie·Leonard BergauPhilipp Sommer
Dec 13, 2019·Journal of Cardiovascular Electrophysiology·Amneet Sandhu, Duy T Nguyen
Nov 13, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Sergio Castrejón-CastrejónJosé Luis Merino
May 12, 2020·Pacing and Clinical Electrophysiology : PACE·Ruhong JiangChenyang Jiang
May 14, 2020·Pacing and Clinical Electrophysiology : PACE·Carola GianniAndrea Natale
Jul 6, 2020·Journal of Cardiovascular Electrophysiology·Jie QiuGuangzhi Chen
Jul 16, 2020·Journal of Cardiovascular Electrophysiology·Junji YamaguchiTetsuo Sasano
Jul 19, 2020·Journal of Cardiovascular Electrophysiology·Roger A Winkle
Aug 7, 2020·Journal of Cardiovascular Electrophysiology·Felix BourierPierre Jais
Aug 19, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Dong Geum ShinHong Euy Lim
Aug 21, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Katharina SchoenePhilipp Sommer
Sep 26, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Shuhei KobayashiJunya Ako
Aug 15, 2019·Journal of Arrhythmia·Hitoshi MoriKazuo Matsumoto
Aug 20, 2019·Journal of Cardiovascular Electrophysiology·Benjamin BerteRichard Kobza
Oct 19, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Tom De PotterPeter Geelen
Dec 25, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Marc KottmaierIsabel Deisenhofer
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