Abstract
Anisakis simplex can elicit allergic reactions when ingested in raw or marinated fish. The prevalence of A simplex hypersensitivity and allergy in Sicily (Italy), an area where the consumption of raw or marinated fish is very common, has not been investigated thus far. To investigate the prevalence of A simplex sensitization and its clinical relevance in a large group of unselected patients. All consecutive patients referred to the authors' allergy clinic during a 22 month-period were included in the study, evaluated for sensitization to A simplex and other allergens depending on their clinical history, and investigated for allergic symptoms after the ingestion of raw or marinated fish. Of 3,419 patients screened, 527 (15.4%) were sensitized to A simplex and 29 of these (5.5% of sensitized patients) had a history of A simplex allergy. Approximately 30% of patients had mono-sensitization to A simplex. Co-sensitization to house dust mites or molds yielded an odds ratio of 1.98 or 3.18, respectively, for allergy to A simplex. A high prevalence of A simplex sensitization in a large proportion of patients with mono-sensitization was found, confirming that eating habits influence sensitization to this nematode. Allergic symptoms from...Continue Reading
References
Jan 1, 1987·Clinical Allergy·P L AmlotM H Lessof
Dec 1, 1996·Journal of Helminthology·L García-PalaciosC Cuéllar
May 1, 1997·Allergy·C Y PascualM Martin-Esteban
Jun 26, 2001·Allergy·B ValiñasF M Ubeira
Jan 28, 2006·Acta Tropica·A Del Rey MorenoJ Lozano Maldonado
May 6, 2006·The Journal of Allergy and Clinical Immunology·Natalie NieuwenhuizenFrank Brombacher
Apr 11, 2008·Clinical Microbiology Reviews·M Teresa Audicana, Malcolm W Kennedy
Jun 19, 2008·Journal of Epidemiology and Community Health·H FalcãoH Barros
May 27, 2010·Foodborne Pathogens and Disease·Ana Isabel Rodríguez-MahilloIgnacio Moneo
Mar 1, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Manuel BoqueteJerónimo Carnés
Jun 10, 2011·Allergy·C GámezV del Pozo
Aug 20, 2011·Allergy·UNKNOWN AAITO-IFIACI Anisakis Consortium
Sep 7, 2011·International Archives of Allergy and Immunology·R AseroD Villalta
Mar 9, 2012·International Archives of Allergy and Immunology·María Luisa CaballeroRosa Rodríguez-Pérez
Apr 25, 2012·Archives of Environmental & Occupational Health·Walter MazzuccoFrancesco Vitale
Jul 3, 2013·International Archives of Allergy and Immunology·Maria Luisa CaballeroRosa Rodriguez-Perez
Nov 14, 2013·Scandinavian Journal of Immunology·A H LinT Van Do
Feb 12, 2014·PLoS Neglected Tropical Diseases·Ivona MladineoFlorencio M Ubeira
Mar 4, 2014·Molecular and Cellular Probes·Fiona J BairdAndreas L Lopata
Apr 1, 2014·Journal of Food Protection·Noelia Carballeda-SangiaoMiguel González-Muñoz
Jul 21, 2014·Current Allergy and Asthma Reports·Natalie E Nieuwenhuizen, Andreas L Lopata
Citations
Aug 25, 2016·Chemico-biological Interactions·Na-Ra HanHyun-Ja Jeong
Jul 19, 2016·Parasite Immunology·Natalie E Nieuwenhuizen
Sep 21, 2018·PloS One·Walter MazzuccoAlessandra Casuccio
Apr 6, 2018·BioMed Research International·Giuseppe A RamirezLorenzo Dagna
Jul 10, 2019·Current Protein & Peptide Science·Ju Yeong KimTai-Soon Yong
Jun 4, 2017·Current Allergy and Asthma Reports·Vivian C NanagasKeerthi R Karamched
Jul 15, 2018·Parasitology Research·María Teresa CorcueraMaría Luisa Caballero
Apr 20, 2019·Frontiers in Immunology·Isabel J Skypala
Oct 8, 2020·Parasitology Research·Amene Raouf RahmatiShokoofeh Shamsi
Mar 28, 2017·Allergologia et immunopathologia·A ArmentiaR Palacios
Aug 29, 2021·Pathogens·Foojan MehrdanaKurt Buchmann