Abstract
To report the microbiological spectrum of conjunctival flora and prevalence of biofilm-forming Methicillin-resistant Staphylococcus aureus (MRSA) in conjunctival flora in chronic dacryocystitis. Prospective, case-control study. We included patients with unilateral chronic dacryocystitis, and their unaffected eyes as control. Microbiological profile and antibiotic susceptibility of the isolates was determined by standard microbiological procedures. S. aureus isolates were further evaluated for Methicillin resistance by Oxacillin resistance screening agar method and mecA polymerase chain reaction (PCR) and for biofilm synthesis by Congo red agar method, Microtitre plate (MTP) assay, and ica A and ica D PCR. We found 95 patients with unilateral chronic dacryocystitis. Aerobic Gram-positive isolates (74.2%, n = 72) were more than Gram-negative (25.7%, n = 25) or anaerobic isolates (20.5%, n = 25). S. aureus was most common (46.4%, n = 45), followed by Pseudomonas aeruginosa (10.3%, n = 10). Gram-positive isolates showed highest sensitivity to Linezolid (100%) and higher generation fluoroquinolones. Gram-negative isolates showed good sensitivity (>90%) to all tested antibiotics. S. aureus isolates showed MRSA prevalence as 93.5% and...Continue Reading
References
Mar 11, 1989·Lancet·P A MapleW Brumfitt
Jul 1, 1994·Journal of Clinical Microbiology·D J GehaD H Persing
May 29, 2001·Journal of Clinical Microbiology·C R ArciolaL Montanaro
Aug 9, 2002·DNA and Cell Biology·Michael E ZegansGeorge O'Toole
Feb 5, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Scott K FridkinUNKNOWN Vancomycin-Intermediate Staphylococcus aureus Epidemiology Study Group
Apr 9, 2005·The Journal of Antimicrobial Chemotherapy·Nathan P WiederholdRussell E Lewis
Sep 30, 2005·Orbit·Daniel BriscoeEhud I Assia
Nov 19, 2005·The Journal of Antimicrobial Chemotherapy·Derek F J BrownUNKNOWN Infection Control Nurses Association
Mar 14, 2007·Antimicrobial Agents and Chemotherapy·Issam RaadRay Hachem
Jul 3, 2007·Eye·M J BharathiS Mittal
Jul 31, 2007·American Journal of Ophthalmology·Julie FreidlinTodd P Margolis
Sep 19, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Scott T Micek
Oct 18, 2007·JAMA : the Journal of the American Medical Association·R Monina KlevensUNKNOWN Active Bacterial Core surveillance (ABCs) MRSA Investigators
Oct 15, 2008·Journal of Microbiological Methods·Amita Jain, Astha Agarwal
Feb 22, 2011·FEMS Immunology and Medical Microbiology·Paul StoodleySandeep Kathju
Mar 26, 2015·Pathogens·Paulo J M BispoMichael S Gilmore
Oct 27, 2015·JAMA Ophthalmology·Penny A AsbellTimothy W Morris
Dec 2, 2017·Eye·C Croghan, D Lockington
Citations
Aug 2, 2019·The Journal of Craniofacial Surgery·Sinan BekmezVecihe Dursun
Jan 9, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Huiling QingLei Han
Jan 13, 2021·BMC Ophthalmology·Ban LuoXiaoqin Yan