High prevalence of cardiovascular risk factors in children and adolescents with type 1 diabetes: a population-based study

Diabetologia
H D MargeirsdottirNorwegian Study Group for Childhood Diabetes

Abstract

The risk of dying of cardiovascular disease (CVD) before the age of 40 years is increased nearly 20-fold in patients with type 1 diabetes compared with non-diabetic persons. The aim of this study was to evaluate the prevalence of CVD risk factors in a population-based study of children and adolescents with type 1 diabetes. CVD risk factors were examined according to the American Diabetes Association criteria in 2005. Of 26 paediatric clinics in Norway, 25 participated with 1,658 patients, 85% of those eligible. Mean age was 13.1 years and mean diabetes duration 5.7 years. HbA(1c) was above the target level in 71.4%. A positive family history of early CVD and/or diabetes was found in 33% of participants. LDL-cholesterol was >2.6 mmol/l in 34.5% and HDL-cholesterol was <1.1 mmol/l in 6.9% of participants. Blood pressure was above the 90th percentile by age, sex and height in 7% and above the 95th percentile in 4% of participants. Four per cent of participants were obese, 3% of those >or=12 years of age reported smoking and 1% of all participants had persistent microalbuminuria. Only 0.2% of the patients were receiving statin and 0.3% anti-hypertensive treatments. Dietary habits and physical activity level were evaluated in some p...Continue Reading

References

Aug 1, 1994·Diabetes Care·D H Wasserman, B Zinman
Feb 7, 2001·Pediatrics·UNKNOWN American Academy of Pediatrics. Committee on Public Education
Apr 11, 2002·Pediatric Pathology & Molecular Medicine·Arthur W ZieskeJack P Strong
Jul 2, 2003·Diabetes Care·UNKNOWN American Diabetes Association
Sep 26, 2003·Scandinavian Journal of Medicine & Science in Sports·L Klasson-Heggebø, S A Anderssen
Nov 6, 2003·JAMA : the Journal of the American Medical Association·Shengxu LiGerald S Berenson
Jan 6, 2004·Journal of Human Hypertension·P H GustavsenK S Kristensen
Aug 3, 2004·Pediatrics·UNKNOWN National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents
Dec 25, 2004·Diabetes Care·UNKNOWN American Diabetes Association
Mar 16, 2005·American Journal of Preventive Medicine·Risto TelamaOlli Raitakari
Apr 28, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·J I MannUNKNOWN Diabetes and Nutrition Study Group (DNSG) of the European Association
Jun 24, 2005·The Journal of Pediatrics·William B StrongFrançois Trudeau
Dec 24, 2005·The New England Journal of Medicine·David M NathanUNKNOWN Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research
Mar 14, 2007·Journal of Hypertension·Giovanni de SimonePaolo Verdecchia
Jun 29, 2007·Medicine and Science in Sports and Exercise·Tuija TammelinSimo Näyhä

❮ Previous
Next ❯

Citations

Mar 8, 2013·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·M TrentoUNKNOWN Piedmont Study Group for Diabetes Epidemiology
Dec 29, 2012·Cardiovascular Diabetology·Fernando M A GiuffridaUNKNOWN Brazilian Type 1 Diabetes Study Group (BrazDiab1SG)
Feb 21, 2013·International Journal of Medical Sciences·Maria Felicia FaienzaLuciano Cavallo
Jul 6, 2014·PloS One·Kenneth Andrew Ross
Dec 19, 2013·Mediators of Inflammation·Joanna TołwińskaArtur Bossowski
Jan 21, 2014·Journal of Nutrition Education and Behavior·Susana R PattonMark A Clements
May 7, 2014·Current Diabetes Reports·Petter Bjornstad, R Paul Wadwa
Mar 17, 2012·European Journal of Pediatrics·Claudia Steigleder-SchweigerEdith Schober
May 30, 2014·Journal of Traditional and Complementary Medicine·Yen-Chang LinPung-Ling Huang
May 16, 2014·Canadian Journal of Diabetes·Diane WherrettDanièle Pacaud
Jun 22, 2012·Journal of Diabetes and Its Complications·Cristiane P MiculisMargaret C S Boguszewski
Mar 30, 2011·Journal of the American Dietetic Association·Susana R Patton
Mar 13, 2010·The Journal of Pediatrics·Mariska van VlietHenk J Veeze
Apr 17, 2010·The Journal of Pediatrics·Beatriz L RodriguezUNKNOWN SEARCH Study Group
Feb 23, 2010·Primary Care Diabetes·Niina MatikainenMarja-Riitta Taskinen
Dec 24, 2015·Diabetes Care·UNKNOWN American Diabetes Association
Sep 29, 2009·Diabetes Research and Clinical Practice·Sorin IoacaraCristina Tiu
May 27, 2008·Lancet·Ravi Retnakaran, Bernard Zinman
Jul 14, 2010·Pediatric Diabetes·K Otfried SchwabUNKNOWN DPV Science Initiative and the Competence Network Diabetes mellitus
Nov 9, 2010·Pediatric Diabetes·Nicole S GlaserUNKNOWN Lawson Wilkins Pediatric Endocrine Society Committee on Drugs and Therapeutics
Mar 25, 2011·Diabetes/metabolism Research and Reviews·Cosimo GianniniC J H Kelnar
Oct 1, 2010·Journal for Specialists in Pediatric Nursing : JSPN·Melissa Spezia Faulkner
Dec 9, 2009·Pediatric Diabetes·Melissa Spezia FaulknerJoseph T Hepworth
May 16, 2014·Diabetes/metabolism Research and Reviews·Orit Pinhas-HamielRachel Frumkin Ben-David
Mar 31, 2016·Pediatric Diabetes·Dionisios ChrysisBessie E Spiliotis
Mar 28, 2013·International Journal of Hypertension·Marilia B GomesLuis Henrique Canani
Aug 6, 2014·Canadian Journal of Diabetes·Javed MohammedFarid H Mahmud
Mar 11, 2015·Pediatric Diabetes·Jacklyn A PivovarovMichael C Riddell
Sep 13, 2014·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·L Golmayo GazteluR Barrio Castellanos
Feb 18, 2012·Diabetes Research and Clinical Practice·Giuliana ValerioUNKNOWN Study-Group on Diabetes of Italian Society of Pediatric Endocrinology and Diabetology (ISPED)
May 7, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Thomas MeissnerReinhard W Holl
Feb 4, 2014·The Journal of Pediatrics·K Otfried SchwabUNKNOWN German/Austrian Diabetes Documentation and Quality Management System (DPV) and the German Health Interview and Examination S
Jul 20, 2016·Diabetology & Metabolic Syndrome·Verônica Medeiros da CostaWilza Arantes Ferreira Peres

❮ Previous
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