High prevalence of gonococcal and chlamydial infection in men who have sex with men with newly diagnosed HIV infection: an opportunity for same-day presumptive treatment

Journal of Acquired Immune Deficiency Syndromes : JAIDS
Katherine C ScottJeffrey D Klausner

Abstract

The increasing use of point-of-care HIV tests in sexually transmitted disease (STD) clinics allows for rapid identification of patients with newly diagnosed HIV infection who may also be at risk for more common sexually transmitted infections. Positive point-of-care HIV test results might be used to identify and provide presumptive treatment to patients who are likely to be coinfected with gonorrhea (GC) and chlamydia (CT). Data from 6864 STD clinic visits by men who have sex with men (MSM) with no history of HIV infection and an HIV antibody test at that visit were analyzed. Results from rectal, pharyngeal, and urine nucleic acid amplification tests were used to calculate the prevalence of infection with GC and CT. MSM with newly diagnosed HIV infection were more likely than HIV-uninfected MSM to be infected with GC (25.9% [53 of 205] vs. 10.9% [728 of 6659]; P < 0.001) and CT (18.5% [38 of 205] vs. 7.8% [518 of 6659]; P < 0.001). GC and CT are common in MSM with newly diagnosed HIV infection at an STD clinic. In this population, a positive point-of-care HIV test result is a useful risk marker for untreated gonococcal and chlamydial infections and provides a justification for presumptive GC and CT treatment.

References

Jan 27, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Sabrina R KendrickRobert A Weinstein
Jun 7, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Charlotte K KentJeffrey D Klausner
Feb 17, 2006·The New England Journal of Medicine·Peter V Chin-HongJeffrey D Klausner

❮ Previous
Next ❯

Citations

Dec 20, 2008·Current Infectious Disease Reports·Kate BuchaczJohn T Brooks
Dec 7, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kenneth H Mayer
Aug 21, 2013·American Journal of Public Health·E Claire NewbernDonald F Schwarz
Jun 15, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marc M SolomonUNKNOWN iPrEx Study Team
Mar 11, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lindley A Barbee, Matthew R Golden
Oct 30, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Guoyu TaoBarbara A Body
Apr 11, 2018·Sexually Transmitted Diseases·Christine M Khosropour, Julia C Dombrowski
Mar 30, 2018·Sexually Transmitted Diseases·Sulayman Aziz, David Sweat
Feb 2, 2010·Sexually Transmitted Diseases·Julia L MarcusJeffrey D Klausner
Jan 18, 2018·International Journal of STD & AIDS·Dan ClutterbuckAnn Sullivan
Nov 7, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jun LiUNKNOWN HIV Outpatient Study (HOPS) Investigators

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.