PMID: 7545630Jul 1, 1995Paper

High prevalence of hepatitis C in Egyptian patients with chronic liver disease

Gut
I A WakedG Thomas Strickland

Abstract

The highest prevalence rates of hepatitis C virus infection in the world have been recently reported among Egyptian blood donors and frequent recipients of transfusions and other blood products. This is the first report, however, demonstrating hepatitis C as the most frequent association with chronic liver disease in Egypt. Of 1023 patients referred to the Liver Institute in Menoufia governorate for evaluation of chronic liver disease, 752 (73.5%) had antibodies to hepatitis C compared with 168 (16.4%) with hepatitis B surface antigen. Hepatitis C antibody was more common in patients with active schistosomiasis and patients without hepatitis B surface antigenaemia. Of 100 patients having liver biopsies, histological findings consistent with chronic viral hepatitis or its complications were found in 89 and antibody to hepatitis C was present in 75 (84.3%) of these patients with chronic hepatitis, active cirrhosis or hepatocellular carcinoma. These data pointing to the importance of hepatitis C as a cause of chronic liver disease in Egypt emphasise the necessity of studies delineating its routes of transmission in this country.

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Citations

Feb 10, 1998·International Journal of Cancer. Journal International Du Cancer·F DonatoM Puoti
Dec 27, 2011·Transactions of the Royal Society of Tropical Medicine and Hygiene·Sayed AbdelwahabG Thomas Strickland
Nov 15, 2001·Transactions of the Royal Society of Tropical Medicine and Hygiene·R E OmerF J Kok
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