PMID: 7336156Jul 1, 1981Paper

High prevalence of increased osmotic fragility of red blood cells among Norwegian blood donors

Scandinavian Journal of Haematology
H C Godal, H Heistø

Abstract

Increased osmotic fragility of red blood cells was found in 9 out of 1008 Norwegian blood donors. In addition, increased osmotic fragility was found in 3 out of 23 first grade relatives and in 1 out of 4 spouses of individuals with the same condition. Finally, there was a positive correlation between increased osmotic fragility and morphological signs of spherocytosis (P less than 0.05). No definite conclusions with respect to underlying mechanism(s) for this high prevalence of non-symptomatic increased osmotic fragility can be offered, but very mild hereditary spherocytosis, environmental factors and even a normal variant, never associated with haemolysis, may have contributed. Furthermore, until more specific and sensitive laboratory techniques have been introduced, a proper distinction between these 3 conditions cannot be made.

References

Jul 1, 1979·Scandinavian Journal of Haematology·H C GodalA Rustad
Jan 1, 1979·Scandinavian Journal of Haematology·H C Godal, H E Refsum
Jan 1, 1977·Acta Medica Scandinavica·O JenssonS Magnússon
Aug 1, 1980·Scandinavian Journal of Haematology·H C GodalF Brosstad
Dec 24, 1960·British Medical Journal·M F CARRUTHERS
Mar 1, 1955·The American Journal of Medicine·L E YOUNG

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Citations

Jan 1, 1992·European Journal of Pediatrics·S CutilloA Iolascon
Jul 1, 1991·European Journal of Haematology·F ZerhouniP Colonna
May 1, 1982·Scandinavian Journal of Haematology·H Heistø, H C Godal
May 19, 2010·Molecular and Cellular Biology·Karina LaflammeDavid M Bodine
Sep 3, 2014·Toxicology Mechanisms and Methods·Ibtissem Ben AmaraNajiba Zeghal
Jan 24, 2017·Toxicology Mechanisms and Methods·Alessandro de Souza PrestesNilda Vargas Barbosa
Feb 13, 2001·British Journal of Haematology·E Miraglia del GiudiceS Perrotta
Aug 4, 2004·British Journal of Haematology·P H B Bolton-MaggsUNKNOWN General Haematology Task Force of the British Committee for Standards in Haematology
Oct 4, 2006·Acta Haematologica·Gudrun StoyaWerner Linss
Nov 25, 2011·Toxicology and Industrial Health·Mohamed MakniNajiba Zeghal
Jun 28, 2011·Molecular Biology Reports·Selen PekerDuygu Ozel Demiralp
Jul 29, 2017·G3 : Genes - Genomes - Genetics·Hong Ming HuangGaetan Burgio
Jun 18, 2020·Clinical Epidemiology·Dennis Lund HansenHenrik Frederiksen
May 30, 2009·Toxicology in Vitro : an International Journal Published in Association with BIBRA·D B SantosN B V Barbosa

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