High prevalence of oncogenic HPV-16 in cervical smears of asymptomatic women of eastern Uttar Pradesh, India: a population-based study.

Journal of Biosciences
Shikha SrivastavaJagat Kumar Roy

Abstract

In developing countries like India, occurrence of Human papillomavirus (HPV) in cervical cancer as well as in the asymptomatic population was observed to be very high. Studies on HPV prevalence have been conducted in different parts of the country but no data were available from the eastern region of Uttar Pradesh (UP). The present study aimed to determine the status of HPV prevalence and its association with different socio-demographic factors in this population. Prevalence of HPV was investigated in a total of 2424 cervical scrape samples of asymptomatic women. Primer sets from L1 consensus region of viral genome were used to detect the presence of HPV, and the positive samples were genotyped by sequencing. Univariate binary logistic regression analysis was used to evaluate association of socio-demographic factors with HPV. 9.9% of the clinically asymptomatic women were found to be infected with HPV comprising 26 different genotypes. Among HPV-positive women, 80.8% showed single infection, while 15.4% harboured multiple infections. HPV-16 (63.7%) was the most prevalent, followed by HPV-31 (6.7%), HPV-6 (5.4%), HPV-81 (4.6%) and HPV-33 (4.2%). Significant association of HPV with non-vegetarian diet (P less than 0.05) and rural...Continue Reading

References

Mar 1, 1995·Journal of Medical Virology·J L VosslerM D Adelson
Apr 1, 1993·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·A G Ostör
Sep 1, 1996·Journal of Clinical Microbiology·F KarlsenB Hagmar
Jan 15, 2003·Clinical Microbiology Reviews·Eileen M Burd
Feb 7, 2003·The New England Journal of Medicine·Nubia MuñozUNKNOWN International Agency for Research on Cancer Multicenter Cervical Cancer Study Group
Jul 5, 2003·Journal of Clinical Microbiology·T VinayagamoorthyRoger Hodkinson
May 5, 2005·British Journal of Cancer·S Franceschi, C Mahé
Sep 29, 2005·BMC Infectious Diseases·Maria G CenturioniClaudio A Gustavino
Jul 13, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Helen TrottierEduardo L Franco
Aug 18, 2006·Microbes and Infection·Rosita VerteramoAnna Marta Degener
Mar 1, 2007·JAMA : the Journal of the American Medical Association·Eileen F DunneLauri E Markowitz
May 24, 2007·British Journal of Cancer·S C CottonUNKNOWN TOMBOLA Group
Feb 26, 2008·Salud pública de México·Yvonne N FloresJorge Salmerón
Jun 27, 2008·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Neerja BhatlaPatti E Gravitt
May 9, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Nicolas WentzensenPhilip E Castle
May 26, 2009·BMC Clinical Pathology·Sin Hang LeeSuri Pappu
Aug 26, 2009·Journal of Women's Health·Keri N AlthoffPatti E Gravitt
Feb 16, 2010·Cancer Epidemiology·Palika DattaNeeta Singh
Dec 15, 2010·Sexual & Reproductive Healthcare : Official Journal of the Swedish Association of Midwives·Shilpa C KerkarJayanti Mania-Pramanik

❮ Previous
Next ❯

Citations

Mar 22, 2016·The Indian Journal of Medical Research·Jaya ChakravartyNisha Rani Agrawal
Apr 7, 2016·International Health·Derek C JohnsonSadeep Shrestha
May 26, 2015·Acta Oto-laryngologica·Christos LoizouKatarina Olofsson
Mar 17, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Shama Prasada KabekkoduKapaettu Satyamoorthy
Jul 15, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Sasidharanpillai SabeenaGovindakarnavar Arunkumar
Apr 5, 2016·Asian Pacific Journal of Cancer Prevention : APJCP·Sasidharanpillai SabeenaGovindakarnavar Arunkumar
Jan 4, 2021·Molecular Biology Reports·Bharti GuptaSridevi Parikipandla
Aug 31, 2021·Seminars in Radiation Oncology·Nicholas Scott-Wittenborn, Carole Fakhry

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Emerging Infectious Diseases
Santiago Pérez Cachafeiro
International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
Andrea Alves RibeiroSilvia Helena Rabelo-Santos
© 2022 Meta ULC. All rights reserved