High pulse pressure protects against headache: prospective and cross-sectional data (HUNT study)

Neurology
E TronvikJ-A Zwart

Abstract

Many antihypertensive drugs are also used as migraine prophylactics, but the relationship between blood pressure and headache is not been well understood. The objective of the present study was to explore the association between blood pressure and headache prevalence, and the effect of antihypertensive medication on this relationship, using both cross-sectional and prospective data from a large population. We used data from two large epidemiologic studies, the Nord-Trøndelag Health Survey 1984-1986 (HUNT-1) and 1995-97 (HUNT-2), to evaluate the association between blood pressure (systolic, diastolic, mean arterial, and pulse pressure) and migraine and nonmigrainous headache. Increasing systolic blood pressure was associated with decreasing prevalence of having nonmigrainous headache or migraine. The most consistent and robust finding, however, was that increasing pulse pressure was linked to decreased prevalence of both nonmigrainous headache and migraine, evident for both sexes in the prospective and cross-sectional analyses. In subjects using antihypertensive medication, this finding was less clear. Both increased systolic blood pressure and pulse pressure are related to arterial stiffness and may decrease headache prevalence...Continue Reading

Citations

Sep 10, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·B S WinsvoldJ-A Zwart
Oct 12, 2010·Future Cardiology·Rui Andre Providencia
Jan 7, 2014·The Journal of Headache and Pain·Erling TronvikKnut Hagen
Mar 17, 2010·Der Internist·J C WöhrleU Woenckhaus
Feb 20, 2013·The Medical Clinics of North America·Charles D Donohoe
Jul 5, 2008·The Journal of Headache and Pain·Simona SaccoAntonio Carolei
Oct 31, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Denise LenskiMichael Böhm
Jul 2, 2009·Acta Neurologica Scandinavica. Supplementum·L J Stovner, K Hagen
Feb 1, 2012·Headache·Andrew D Hershey
Nov 14, 2012·British Journal of Clinical Pharmacology·Emma J TurtleDavid J Webb
May 22, 2009·Acta Neurologica Scandinavica·K B NilsenL J Stovner
Feb 18, 2010·Pain Practice : the Official Journal of World Institute of Pain·Yaprak SeçilMustafa Başoğlu
Aug 27, 2014·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C F FagernæsK Hagen
Nov 18, 2014·Clinical Oral Investigations·Christophe DeschaumesRadhouane Dallel
Dec 30, 2014·Journal of Clinical Anesthesia·Alejandro E DelfinoLuis I Cortinez
Oct 27, 2010·Cephalalgia : an International Journal of Headache·Han LeJes Olesen
Dec 17, 2014·Cephalalgia : an International Journal of Headache·Simona SaccoAntonio Carolei
Apr 22, 2015·Cephalalgia : an International Journal of Headache·Lasse-Marius HonningsvågMattias Linde
Jul 14, 2012·São Paulo Medical Journal = Revista Paulista De Medicina·José Marcos ThalenbergRui Manuel dos Santos Póvoa
Aug 10, 2010·Cephalalgia : an International Journal of Headache·Isabela M BenseñorMárcia Scazufca
Apr 6, 2018·Current Pain and Headache Reports·Innocenzo RaineroElisa Rubino
Feb 2, 2018·Cephalalgia : an International Journal of Headache·Pamela M RistTobias Kurth
Feb 1, 2020·Journal of Hypertension·Dmitry M Davydov
Jul 17, 2021·Current Pain and Headache Reports·Yen-Feng Wang, Shuu-Jiun Wang

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