High-Quality Genome Reconstruction of Candida albicans CHN1 Using Nanopore and Illumina Sequencing and Hybrid Assembly.

Microbiology Resource Announcements
Shipra GargGary B Huffnagle

Abstract

We report an improved, nearly closed, high-quality draft genome reconstruction of the Candida albicans CHN1 strain (ATCC MYA-4779), a human isolate, using Illumina and Nanopore sequencing. Covering six complete and two partial nuclear chromosomes along with a partial mitochondrial genome, this assembly is 14,787,852 bases in size, with 5,935 genes.

References

Jul 3, 2004·Genome Research·Aaron C E DarlingNicole T Perna
Aug 24, 2004·Infection and Immunity·Mairi C NoverrGary B Huffnagle
Sep 10, 2011·Bioinformatics·Tanja Magoč, Steven L Salzberg
Feb 21, 2013·Bioinformatics·Alexey GurevichGlenn Tesler
Jul 13, 2013·Scientific Reports·John R Erb DownwardGary B Huffnagle
Jun 11, 2015·Bioinformatics·Felipe A SimãoEvgeny M Zdobnov
Jan 27, 2018·PLoS Computational Biology·Guillaume MarçaisAleksey Zimin
Mar 17, 2018·Bioinformatics·Wouter De CosterChristine Van Broeckhoven
Apr 3, 2019·Nature Biotechnology·Mikhail KolmogorovPavel A Pevzner

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Software Mentioned

FLASH
Cutadapt
MUMmer
Mauve
NanoPlot
Guppy
QUAST
BWA
Flye
BUSCO

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