High rate of abnormal glucose tolerance in Brazilian individuals undergoing coronary angiography

Archives of Endocrinology and Metabolism
Valdecira M PivetaAndré F Reis

Abstract

Undiagnosed hyperglycemia is common in high cardiovascular risk individuals, especially in those with coronary artery disease (CAD). There is no consensus about the optimal method for the screening of hyperglycemia in this population. Five hundred and fourteen Brazilian individuals undergoing coronary angiography, without previously known diabetes mellitus (DM), had their glycemic status evaluated by both fasting plasma glucose (FPG) and HbA1c, being classified in normal (N), prediabetes (PD), and DM according to American Diabetes Association criteria. Concordance between both methods was assessed by Cohen's κ. Accuracy of FPG and HbA1c to diagnose CAD was evaluated as proof-of-concept. Among individuals screened by FPG, 41.2% had PD and 6% had DM. Among those screened by HbA1c, 52.7% had PD and 12.7% had DM. Concordance for a positive screening of PD occurred in 125 individuals (κ = 0.084). Eighteen individuals had a concordant positive screening of DM (κ = 0.310). As a predictor of CAD, accuracy of FPG was 0.554 (p = 0.009) and of HbA1c 0.557 (p = 0.006). a high frequency of hyperglycemia, between 47 and 65%, was found in individuals submitted to coronary angiography without previously known glucose disturbances, using FPG an...Continue Reading

References

Sep 21, 2006·European Heart Journal·Da-Yi HuUNKNOWN China Heart Survey Group
Jan 3, 2012·Diabetes & Metabolism·B VergèsUNKNOWN Diabetes and Cardiovascular Disease study group of the Société francophone du diabète (SFD), in collaboration with the Socié
Jan 4, 2013·Diabetes Care·UNKNOWN American Diabetes Association

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