High rate of percutaneous endoscopic gastrostomy site infections due to oropharyngeal colonization

Digestive Diseases and Sciences
Sandra FaiasCarlos Nobre-Leitão

Abstract

We prospectively analyzed peristomal infection agents during the first week following percutaneous endoscopic gastrostomy (PEG) placement by the pull technique in patients with head and neck cancer. Nasal and pharyngeal swabs were obtained from a consecutive series of cancer patients prior to PEG placement. All patients underwent antibiotic prophylaxis with cefotaxime and oral disinfection. PEG site infection was prospectively evaluated at days 2, 3, and 7 after insertion. Twenty-eight patients (25 males; mean age, 58 years) were included. Oropharyngeal or nasal colonization were observed in 68% (19/28) and 19% (5/28) of patients, respectively. Early infections occurred in 36% (10/28) of the patients, all with oropharyngeal colonization and concordance between agents (P=0.01). Three patients required hospital admission and 1 required surgery. Head and neck cancer patients with oropharyngeal colonization have a high risk of early PEG site infection with substantial morbidity owing to oral-stomal spread.

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Citations

Oct 10, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Chiao-Hsiung ChuangBor-Shyang Sheu
Dec 8, 2009·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Alastair CairnsChristopher Babbs
Dec 31, 2010·High Altitude Medicine & Biology·Sven HungererVolker Bühren
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Jan 31, 2012·Infectious Disease Clinics of North America·Christopher J Crnich, Paul Drinka
Apr 1, 2008·Journal of Vascular and Interventional Radiology : JVIR·Colin P CantwellPeter R Mueller
Mar 25, 2016·The Indian Journal of Surgery·Savas YurukerNecati Ozen
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May 11, 2010·Journal of Pediatric Gastroenterology and Nutrition·Christian BraeggerJohannes van Goudoever

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