High ratio of triglycerides to HDL-cholesterol predicts extensive coronary disease.

Clinics
Protasio Lemos da LuzAntonio Carlos Palandri Chagas

Abstract

An abnormal ratio of triglycerides to HDL-cholesterol (TG/HDL-c) indicates an atherogenic lipid profile and a risk for the development of coronary disease. To investigate the association between lipid levels, specifically TG/HDL-c, and the extent of coronary disease. High-risk patients (n=374) submitted for coronary angiography had their lipid variables measured and coronary disease extent scored by the Friesinger index. The subjects consisted of 220 males and 154 females, age 57.2+/-11.1 years, with total cholesterol of 210+/-50.3 mg/dL, triglycerides of 173.8+/-169.8 mg/dL, HDL-cholesterol (HDL-c) of 40.1+/-12.8 mg/dL, LDL-cholesterol (LDL-c) of 137.3+/-46.2 mg/dL, TG/HDL-c of 5.1+/-5.3, and a Friesinger index of 6.6+/-4.7. The relationship between the extent of coronary disease (dichotomized by a Friesenger index of 5 and lipid levels (normal vs. abnormal) was statistically significant for the following: triglycerides, odds ratio of 2.02 (1.31-3.1; p=0.0018); HDL-c, odds ratio of 2.21 (1.42-3.43; p=0.0005); and TG/HDL-c, odds ratio of 2.01(1.30-3.09; p=0.0018). However, the relationship was not significant between extent of coronary disease and total cholesterol [1.25 (0.82-1.91; p=0.33)] or LDL-c [1.47 (0.96-2.25; p=0.0842)...Continue Reading

Citations

Sep 6, 2020·Journal of Clinical Medicine·Sung Mi JungSe Kyung Lee
Sep 6, 2019·Journal of Diabetes Research·Chase M WaltonBenjamin T Bikman
Aug 23, 2016·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Kumiko TorisuYusaku Nakabeppu
Jul 16, 2016·Journal of Tropical Medicine·Clara WekesaAnatoli Kamali
Nov 22, 2018·The Journal of Clinical Hypertension·Xiaojuan LiuFuzhong Xue
Dec 20, 2012·International Journal of Endocrinology·Ahmet Levent BasEzgi Ermis Kaya
Aug 3, 2020·Journal of Strength and Conditioning Research·Hunter S WaldmanMatthew J McAllister
Oct 1, 2020·BMC Cardiovascular Disorders·Huichen YaoQingzhi Hou
Aug 25, 2019·Animals : an Open Access Journal From MDPI·Biagina ChiofaloCristina Cravana
Apr 7, 2017·Journal of Paediatrics and Child Health·Elim ManYiu-Fai Cheung
Jun 18, 2017·Archivos de cardiología de México·Lorena UrbanoCarlos H Sierra-Torres
Jan 10, 2017·Alcoholism, Clinical and Experimental Research·Mariann R PianoShane A Phillips
Feb 16, 2021·Journal of Medical Biochemistry·Aleksandra KlisićAna Ninić
Dec 7, 2016·World Journal of Gastroenterology : WJG·Ivana MikolasevicLidija Orlic
Apr 4, 2021·International Journal of Molecular Sciences·Ramilya Z MurtazinaRaul R Gainetdinov
Jun 28, 2015·Clinica Chimica Acta; International Journal of Clinical Chemistry·Jonatas Zeni KlafkePaulo Ricardo Nazário Viecili
Jul 31, 2021·Quality Management in Health Care·Orit GoldmanMoshe Leshno

❮ Previous
Next ❯

Methods Mentioned

BETA
electrophoresis
nuclear magnetic resonance

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.