PMID: 6411064Jun 1, 1983Paper

High resolution 1H n.m.r. studies of vertebrate blood and plasma

The Biochemical Journal
J K NicholsonP J Sadler

Abstract

Spin echo Fourier transform proton n.m.r. spectra of whole blood contain resonances from both erythrocytes and plasma. A large number of well-resolved signals from mobile protons of low-molecular-weight metabolites in plasma and serum have been identified. Spectra from the plasmas of eight animal species and commercial, quality control sera are compared. CaEDTA2- and MgEDTA2- resonances can be used for the simultaneous determination of EDTA-chelatable calcium and magnesium concentrations in intact plasma and other biological fluids. Cholesterol is too immobile to contribute to the spectra of intact plasma, but is readily estimated by n.m.r. in both its free and esterified forms after extraction into methanol.

Citations

Jul 26, 2006·Expert Opinion on Drug Metabolism & Toxicology·Donald G RobertsonJ David Baker
Mar 10, 2016·Progress in Nuclear Magnetic Resonance Spectroscopy·Teresa W-M Fan, Andrew N Lane
Apr 2, 2013·Progress in Nuclear Magnetic Resonance Spectroscopy·Roger MallolXavier Correig
Feb 18, 2016·Analytical Chemistry·Maninder SinghNarayanan D Kurur
Sep 8, 2015·Archives of Biochemistry and Biophysics·Ning LiYulan Wang
Mar 5, 2015·Analytical and Bioanalytical Chemistry·Peiyuan YinGuowang Xu
Jun 9, 2016·Oxidative Medicine and Cellular Longevity·Mengting LiuHongjun Yang
Mar 20, 2013·Chemical Reviews·Naomi L Kuehnbaum, Philip Britz-McKibbin
Jan 1, 1989·Free Radical Research Communications·M Grootveld, R Jain
Mar 18, 2017·Systems Biology in Reproductive Medicine·Forough EbrahimiKit-Lam Chan
Jan 1, 1987·Journal of Inherited Metabolic Disease·R D Griffiths, R H Edwards
Jul 1, 2009·Future Medicinal Chemistry·Anthony D MaherJeremy K Nicholson
Apr 1, 1988·NMR in Biomedicine·J D BellD R Newell
Mar 7, 2017·Archives of Biochemistry and Biophysics·Andrew N Lane, Teresa W-M Fan
Jul 1, 2007·Journal of Diabetes Science and Technology·Johan H FaberDorrit Baunsgaard
Feb 25, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Peter RasmussenBjørn Quistorff
Mar 11, 2018·Archives of Pharmacal Research·Jong-Jae YiWoo Sung Son
Jul 18, 2002·Nature Reviews. Drug Discovery·Jeremy K NicholsonElaine Holmes
Jan 1, 1989·Archives of Toxicology·K P GartlandJ K Nicholson
Jul 1, 1989·NMR in Biomedicine·J K Nicholson, K P Gartland
Dec 1, 1989·NMR in Biomedicine·J D BellP J Sadler
Dec 1, 1986·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J R BalesP J Sadler
May 1, 1987·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S ConnorJ K Nicholson
Mar 1, 1988·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J R BalesR Williams
Jun 1, 1987·Prenatal Diagnosis·T R NelsonD H Pretorius
Jan 1, 1989·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·I M BreretonD M Doddrell
Sep 1, 2011·Molecular Systems Biology·George NicholsonChris C Holmes

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