High-resolution diffusion tensor imaging for the detection of diffusion abnormalities in the trigeminal nerves of patients with trigeminal neuralgia caused by neurovascular compression

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
Shunrou FujiwaraKuniaki Ogasawara

Abstract

To detect diffusion abnormalities in the trigeminal nerves of patients with trigeminal neuralgia (TN) caused by neurovascular compression (NVC) by using a high-resolution diffusion tensor imaging (HR-DTI) technique. Thirteen patients with TN and 14 healthy controls underwent HR-DTI scanning. After extracting the trigeminal nerve using a tractography technique, we measured the fractional anisotropy (FA) and apparent diffusion coefficient (ADC), and compared the contralateral ratios (CR) of these parameters between the patients and controls, and correlated these ratios with the cross-sectional areas of the nerves. The CRs of the FA values for the trigeminal nerves of the patients (1.00±0.15) had significantly higher variance than those of healthy controls (1.00±0.05) (P<.05) and showed a positive correlation with the cross-sectional area of the nerves (r=0.81). In contrast, the CRs of the ADC values were not significantly different between the two groups (1.02±0.10 and 1.01±0.08, respectively) and had no significant correlation with cross-sectional area. HR-DTI can detect an alteration in the relative FA values of affected trigeminal nerves and a correlation with atrophic changes in patients with NVC-induced TN.

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Citations

Jul 25, 2012·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Karen D Davis, Massieh Moayedi
Mar 7, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Alessandro TrebbastoniCarlo de Lena
May 21, 2013·The Journal of Pain : Official Journal of the American Pain Society·Sophie L WilcoxLuke A Henderson
Nov 1, 2015·Clinical Neurology and Neurosurgery·Patrick W HitchonJennifer Noeller
Nov 20, 2014·International Journal of Computer Assisted Radiology and Surgery·Masanori YoshinoNobuhito Saito
Dec 14, 2018·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Sandip S PanesarJuan Fernandez-Miranda
Jun 15, 2011·Journal of Dental Research·A F DaSilva, M F DosSantos
Jul 17, 2018·Neurosurgery·Timothée JacquessonFrancois Cotton
Mar 2, 2021·Frontiers in Neurology·Hayden DanylukTejas Sankar
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