High-resolution genomic analysis: the tumor-immune interface comes into focus

Genome Biology
Jonathan J Havel, Timothy A Chan

Abstract

A genomic analysis of heterogeneous colorectal tumor samples has uncovered interactions between immunophenotype and various aspects of tumor biology, with implications for informing the choice of immunotherapies for specific patients and guiding the design of personalized neoantigen-based vaccines.

References

Oct 26, 2005·Proceedings of the National Academy of Sciences of the United States of America·Volker LennerzThomas Wölfel
Jun 5, 2012·The New England Journal of Medicine·Suzanne L TopalianMario Sznol
Sep 18, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nienke van RooijTon N Schumacher
Nov 20, 2014·The New England Journal of Medicine·Alexandra SnyderTimothy A Chan
Feb 26, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michele MaioJedd D Wolchok

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Citations

Apr 12, 2016·Frontiers in Immunology·Yannick De VlaeminckKarine Breckpot

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Methods Mentioned

BETA
RNA-seq

Related Concepts

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