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High-resolution mapping of expression-QTLs yields insight into human gene regulation

PLoS Genetics

Oct 1, 2008

Jean-Baptiste VeyrierasJonathan K. Pritchard

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Abstract

Recent studies of the HapMap lymphoblastoid cell lines have identified large numbers of quantitative trait loci for gene expression (eQTLs). Reanalyzing these data using a novel Bayesian hierarchical model, we were able to create a surprisingly high-resolution map of the typical locatio...read more

Mentioned in this Paper

DNA Probe Method
ATM wt Allele
Gene Expression
DNA Sequence
Probe brand of methazole herbicide
probe gene fragment
Online Mendelian Inheritance In Man
Study of Epigenetics
Nucleic Acid Hybridization Procedure
Quantitative Trait Loci
1
410
1
Paper Details
References
    • References46
    • Citations260
    • References46
    • Citations260
  • High-resolution mapping of expression-QTLs yields insight into human gene regulation

    PLoS Genetics

    Oct 1, 2008

    Jean-Baptiste VeyrierasJonathan K. Pritchard

    PMID: 18846210

    DOI: 10.1371/journal.pgen.1000214

    Abstract

    Recent studies of the HapMap lymphoblastoid cell lines have identified large numbers of quantitative trait loci for gene expression (eQTLs). Reanalyzing these data using a novel Bayesian hierarchical model, we were able to create a surprisingly high-resolution map of the typical locatio...read more

    Mentioned in this Paper

    DNA Probe Method
    ATM wt Allele
    Gene Expression
    DNA Sequence
    Probe brand of methazole herbicide
    1
    410
    1
    Paper Details
    References
    • References46
    • Citations260
    • References46
    • Citations260
  • Get paper from

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